Quantifying brain microstructure with diffusion MRI: Theory and parameter estimation

DS Novikov, E Fieremans, SN Jespersen… - NMR in …, 2019 - Wiley Online Library
We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …

Imaging brain microstructure with diffusion MRI: practicality and applications

DC Alexander, TB Dyrby, M Nilsson… - NMR in …, 2019 - Wiley Online Library
This article gives an overview of microstructure imaging of the brain with diffusion MRI and
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …

[HTML][HTML] Can MRI measure myelin? Systematic review, qualitative assessment, and meta-analysis of studies validating microstructural imaging with myelin histology

A Lazari, I Lipp - Neuroimage, 2021 - Elsevier
Recent years have seen an increased understanding of the importance of myelination in
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …

A review of diffusion MRI of typical white matter development from early childhood to young adulthood

C Lebel, S Treit, C Beaulieu - NMR in Biomedicine, 2019 - Wiley Online Library
Understanding typical, healthy brain development provides a baseline from which to detect
and characterize brain anomalies associated with various neurological or psychiatric …

An interactive meta-analysis of MRI biomarkers of myelin

M Mancini, A Karakuzu, J Cohen-Adad, M Cercignani… - elife, 2020 - elifesciences.org
Several MRI measures have been proposed as in vivo biomarkers of myelin, each with
applications ranging from plasticity to pathology. Despite the availability of these myelin …

[HTML][HTML] Multi-compartment microscopic diffusion imaging

E Kaden, ND Kelm, RP Carson, MD Does… - NeuroImage, 2016 - Elsevier
This paper introduces a multi-compartment model for microscopic diffusion anisotropy
imaging. The aim is to estimate microscopic features specific to the intra-and extra-neurite …

Design and validation of diffusion MRI models of white matter

IO Jelescu, MD Budde - Frontiers in physics, 2017 - frontiersin.org
Diffusion MRI is arguably the method of choice for characterizing white matter microstructure
in vivo. Over the typical duration of diffusion encoding, the displacement of water molecules …

[HTML][HTML] Challenges for biophysical modeling of microstructure

IO Jelescu, M Palombo, F Bagnato… - Journal of Neuroscience …, 2020 - Elsevier
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

[HTML][HTML] White matter microstructure across the adult lifespan: A mixed longitudinal and cross-sectional study using advanced diffusion models and brain-age …

D Beck, AMG de Lange, II Maximov, G Richard… - NeuroImage, 2021 - Elsevier
The macro-and microstructural architecture of human brain white matter undergoes
substantial alterations throughout development and ageing. Most of our understanding of …

[HTML][HTML] Diffusion-weighted imaging: recent advances and applications

E Martinez-Heras, F Grussu, F Prados, E Solana… - Seminars in Ultrasound …, 2021 - Elsevier
Quantitative diffusion imaging techniques enable the characterization of tissue
microstructural properties of the human brain “in vivo”, and are widely used in neuroscientific …