Current status of Clonorchis sinensis and clonorchiasis in China

DH Lai, XK Hong, BX Su, C Liang… - Transactions of the …, 2016 - academic.oup.com
The oriental liver fluke, Clonorchis sinensis, a pathogen causing clonorchiasis, is of major
socio-economic importance in East Asia, including China, Korea and Vietnam. This parasite …

Surveillance and diagnosis of zoonotic foodborne parasites

R Zolfaghari Emameh, S Purmonen… - Food science & …, 2018 - Wiley Online Library
Foodborne parasites are a source of human parasitic infection. Zoonotic infections of
humans arise from a variety of domestic and wild animals, including sheep, goats, cattle …

Glucose transporters and sodium glucose co-transporters cooperatively import glucose into energy-demanding organs in carcinogenic liver fluke Clonorchis sinensis

F Dai, SO Lee, JH Song, WG Yoo, EH Shin… - PLoS neglected …, 2024 - journals.plos.org
Background The liver fluke Clonorchis sinensis imports large amounts of glucose to
generate energy and metabolic intermediates through glycolysis. We hypothesized that C …

Sodium-bile acid co-transporter is crucial for survival of a carcinogenic liver fluke Clonorchis sinensis in the bile

F Dai, WG Yoo, Y Lu, JH Song, JY Lee… - PLoS neglected …, 2020 - journals.plos.org
The liver fluke Clonorchis sinensis inhabits the bile ducts, where bile concentration
disparities across the fluke cell membrane can cause bile intoxication. Sodium-bile acid co …

Characterization of a novel organic solute transporter homologue from Clonorchis sinensis

Y Lu, WG Yoo, F Dai, JY Lee, JH Pak… - PLoS Neglected …, 2018 - journals.plos.org
Clonorchis sinensis is a liver fluke that can dwell in the bile ducts of mammals. Bile acid
transporters function to maintain the homeostasis of bile acids in C. sinensis, as they induce …

Serodiagnostic antigens of Clonorchis sinensis identified and evaluated by high-throughput proteogenomics

PY Cho, JY Lee, TI Kim, JH Song… - PLoS neglected …, 2020 - journals.plos.org
Clonorchiasis caused by Clonorchis sinensis is endemic in East Asia; approximately 15
million people have been infected thus far. To diagnose the infection, serodiagnostic tests …

Molecular and Structural Characterization of the Tegumental 20.6-kDa Protein in Clonorchis sinensis as a Potential Druggable Target

YJ Kim, WG Yoo, MR Lee, JM Kang, BK Na… - International Journal of …, 2017 - mdpi.com
The tegument, representing the membrane-bound outer surface of platyhelminth parasites,
plays an important role for the regulation of the host immune response and parasite survival …

Genomic and transcriptomic analyses of Clonorchis sinensis infection

GN Chelomina - Molecular Medical Microbiology, 2024 - Elsevier
This chapter reviews our current knowledge about genomics and transcriptomics of the
Chinese liver fluke Clonorchis sinensis, a causative agent of severe hepatobiliary diseases …

The omic approach to parasitic trematode research—a review of techniques and developments within the past 5 years

O Haçarız, GP Sayers - Parasitology research, 2016 - Springer
The evolution of technologies to explore parasite biology at a detailed level has made
significant advances in recent years, particularly with the development of omic-based …

Molecular and structural characteristics of multidrug resistance-associated protein 7 in Chinese liver fluke Clonorchis sinensis

F Dai, WG Yoo, JY Lee, Y Lu, JH Pak, WM Sohn… - Parasitology …, 2017 - Springer
Multidrug resistance-associated protein 7 (MRP7, ABCC10) is a C subfamily member of the
ATP-binding cassette (ABC) superfamily. MRP7 is a lipophilic anion transporter that pumps …