MBOAT7 is a protein anchored to endomembranes by several transmembrane domains. It
has a catalytic dyad involved in remodelling of phosphatidylinositol with polyunsaturated …

Liquid biopsies have emerged as a minimally invasive cancer detection and monitoring
method, which could identify cancer-related alterations in nucleosome or histone levels and …

Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by a
constant accumulation of lipids in the liver. This hepatic lipotoxicity is associated with a …

Purpose Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
in the world. However, biomarkers for NAFLD diagnosis and liver-specific drugs for …

Introduction: Pediatric brain tumours (PBT) are one of the most common malignancies
during childhood, with variable severity according to the location and histological type …

Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) is a growing epidemic
with an estimated prevalence of 20%–30% in Europe and the most common cause of …

Background Diffuse midline glioma, H3 K27-altered (DMG) is a fatal tumour that arises in the
midline structures of the brain. When located in the pons, it is more commonly referred to as …

Liver diseases are a major burden worldwide, the scope of which is expected to further grow
in the upcoming years. Clinically relevant liver dysfunction-related blood markers such as …

Metabolic diseases affect a consistent part of the human population, leading to rising
mortality rates. This raises the need for diagnostic tools to monitor the progress of these …

Epigenetics refers to the process of modulating gene expression through changes in DNA or
its associated factors (without altering the DNA sequence). Epigenetic factors, collectively …