The prospect of gene therapy for inherited and acquired respiratory disease has energized
the research community since the 1980s, with cystic fibrosis, as a monogenic disorder …

Efficient manufacture of recombinant adeno-associated virus (rAAV) vectors for gene
therapy remains challenging. Packaging cell lines containing stable integration of the AAV …

SARS‐CoV‐2 is a newly emerged coronavirus, causing the global pandemic of respiratory
coronavirus disease (COVID‐19). The type I interferon (IFN) pathway is of particular …

Adeno-associated viruses (AAVs) are leading platforms for in vivo delivery of gene
therapies, with six licensed AAV-based therapeutics attributed to their non-pathogenic …

Infectious viral particles in bioaerosols generated during laparoscopic surgery place staff
and patients at significant risk of infection and contributed to the postponement of countless …

A lentiviral vector (LV) pseudotype derived from the fusion (F) and hemagglutinin-
neuraminidase (HN) glycoproteins of a murine respirovirus (Sendai virus) facilitates efficient …

Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) poses a significant socioeconomic burden, and …

Vaccines for COVID-19 are now a crucial public health need, but the degree of protection
provided by conventional vaccinations for individuals with compromised immune systems is …

The presence of infectious viral particles in bioaerosols generated during laparoscopic
surgery places surgical staff at significant risk of infection and represents a major cause of …