Myocardial infarction is the most common cause of cardiac injury and results in acute loss of
a large number of myocardial cells. Because the heart has negligible regenerative capacity …

Cell-based cardiac repair offers the promise of rebuilding the injured heart from its
component parts. Work began with committed cells such as skeletal myoblasts, but recently …

Bone marrow derived mesenchymal stem cells (BM-MSCs) have been shown to enhance
wound healing; however, the mechanisms involved are barely understood. In this study, we …

Myocardial infarction is a leading cause of mortality worldwide. Here we report that
modulation of microRNA-499 (miR-499) levels affects apoptosis and the severity of …

Cardiac hypertrophy occurs as an adaptive response to increased workload to maintain
cardiac function. However, prolonged cardiac hypertrophy causes heart failure, and its …

This article is focused on reviewing the current state-of-the-art of optical fibre pressure
sensors for medical applications. Optical fibres have inherent advantages due to their small …

Following an acute myocardial infarction (AMI), early coronary artery reperfusion remains
the most effective means of limiting the eventual infarct size. The resultant left ventricular …

Neutrophils are phagocytes whose principal function is to maintain anti-bacterial immunity.
Neutrophils ingest and kill invading bacteria, releasing cytotoxic, chemotactic and …

Thanks to the development of new, more potent and selective immunosuppressive drugs
together with advances in surgical techniques, organ transplantation has emerged from an …

After the onset of ischemia, cardiac or skeletal muscle undergoes a continuum of molecular,
cellular, and extracellular responses that determine the function and the remodeling of the …