The development of solid phase peptide synthesis has released tremendous opportunities
for using synthetic peptides in medicinal applications. In the last decades, peptide …

Macromolecular protein and peptide therapeutics have been proven to be effective in
treating critical human diseases precisely. Thanks to biotechnological advancement, a huge …

The practical application of nanoparticles (NPs) as chemotherapeutic drug delivery systems
is often hampered by issues such as poor circulation stability and targeting inefficiency …

With the development of modern chemistry and biology, non-proteinogenic amino acids
(NPAAs) have become a powerful tool for developing peptide-based drug candidates. Drug …

Cell membranes have recently emerged as a new source of materials for molecular delivery
systems. Cell membranes have been extruded or sonicated to make nanoscale vesicles …

Building upon the resounding therapeutic success of monoclonal antibodies, and supported
by accelerating progress in engineering methods, the field of multispecific therapeutic …

Peptides and small protein scaffolds are gaining increasing interest as therapeutics.
Similarly to full-length antibodies, they can bind a target with a high binding affinity and …

Antimicrobial peptides (AMPs) constitute promising alternatives to classical antibiotics for the
treatment of drug-resistant infections, which are a rapidly emerging global health challenge …

Structural variety, tunable porosity and opportunities for functionalization make metal‐
organic frameworks (MOFs) promising materials for applications in medicine as drug …

Chemical Strategies for Half-Life Extension of Biopharmaceuticals: Lipidation and Its
Alternatives | ACS Medicinal Chemistry Letters ACS ACS Publications C&EN CAS Find my …