Kaempferol as a therapeutic agent in Alzheimer's disease: Evidence from preclinical studies

X Dong, S Zhou, J Nao - Ageing research reviews, 2023 - Elsevier
Background Alzheimer's disease (AD) is the most common type of dementia and seriously
affects human life and health. Kaempferol (KMP) is a common flavonoid, that is mainly …

A comprehensive review of machine learning algorithms and their application in geriatric medicine: present and future

RJ Woodman, AA Mangoni - Aging Clinical and Experimental Research, 2023 - Springer
The increasing access to health data worldwide is driving a resurgence in machine learning
research, including data-hungry deep learning algorithms. More computationally efficient …

Effects of neural stem cell transplantation in Alzheimer's disease models

Y Hayashi, HT Lin, CC Lee, KJ Tsai - Journal of biomedical science, 2020 - Springer
Currently there are no therapies for treating Alzheimer's disease (AD) that can effectively halt
disease progression. Existing drugs such as acetylcholinesterase inhibitors or NMDA …

An improved LeNet-deep neural network model for Alzheimer's disease classification using brain magnetic resonance images

RA Hazarika, A Abraham, D Kandar, AK Maji - IEEE Access, 2021 - ieeexplore.ieee.org
Alzheimer's Disease (AD) is a psychological disorder in elderly people which causes severe
intellectual disabilities. Proper processing of neuro-images can provide differences in brain …

[HTML][HTML] Evolution of Alzheimer's disease research from a health-tech perspective: Insights from text mining

DD Martinelli - International Journal of Information Management Data …, 2022 - Elsevier
Tens of thousands of publications have addressed the global threat posed by Alzheimer's
disease (AD), traversing the boundaries of discipline to provide novel insight into the …

Recent advances in Alzheimer's disease pathogenesis and therapeutics from an immune perspective

TD Nguyen, LN Dang, JH Jang, S Park - Journal of Pharmaceutical …, 2023 - Springer
Abstract Background The prevalence of Alzheimer's disease, the most common type of
dementia, is continuously increasing. Many recent reports have indicated that immune …

Wistar rats hippocampal neurons response to blood low-density polyethylene microplastics: a pathway analysis of SOD, CAT, MDA, 8-OHdG expression in …

Y Sincihu, MFD Lusno, TM Mulyasari… - Neuropsychiatric …, 2023 - Taylor & Francis
Purpose Low-density polyethylene microplastics are ingested into the bloodstream and
distributed to all the organ tissue, including the hippocampus, causing toxic effects. This …

Effects of Exercise in the Treatment of Alzheimer's Disease: an umbrella review of systematic reviews and meta-analyses

A Andrade, TC Siqueira… - Journal of Aging …, 2021 - journals.humankinetics.com
The authors aimed to provide an overview of the evidence on the effects of exercise in
people with Alzheimer's disease through a comprehensive review of the existing systematic …

Decanoic Acid Rescues Differences in AMPA-Mediated Calcium Rises in Hippocampal CA1 Astrocytes and Neurons in the 5xFAD Mouse Model of Alzheimer's …

M Abghari, JTCM Vu, N Eckberg, BI Aldana… - Biomolecules, 2023 - mdpi.com
Alzheimer's disease (AD), a devastating neurodegenerative disease characterized by
cognitive dysfunctions, is associated with high levels of amyloid beta 42 (Aβ42), which is …

Is air pollution associated with increased risk of dementia? a meta-analysis of epidemiological research

V Dhiman, T Trushna, D Raj, RR Tiwari - Neurology India, 2022 - journals.lww.com
Background: There are prevailing inconsistencies in epidemiological research about air
pollution being a risk factor for dementia. Objective: We performed meta-analyses to …