HY5: A pivotal regulator of light-dependent development in higher plants

Y Xiao, L Chu, Y Zhang, Y Bian, J Xiao… - Frontiers in plant …, 2022 - frontiersin.org
ELONGATED HYPOCOTYL5 (HY5), a bZIP-type transcription factor, acts as a master
regulator that regulates various physiological and biological processes in plants such as …

E3 ubiquitin ligases: ubiquitous actors in plant development and abiotic stress responses

K Shu, W Yang - Plant and Cell Physiology, 2017 - academic.oup.com
Understanding the precise regulatory mechanisms of plant development and stress
responses at the post-translational level is currently a topic of intensive research. Protein …

The activities of the E3 ubiquitin ligase COP1/SPA, a key repressor in light signaling

U Hoecker - Current opinion in plant biology, 2017 - Elsevier
Highlights•The COP1/SPA complex suppresses light signaling in darkness.•Functions of the
protein domains in COP1 and SPA proteins.•The structure of the COP1 WD-repeat domain …

A regulatory module controlling homeostasis of a plant immune kinase

J Wang, LE Grubb, J Wang, X Liang, L Li, C Gao, M Ma… - Molecular cell, 2018 - cell.com
Plant pattern recognition receptors (PRRs) perceive microbial and endogenous molecular
patterns to activate immune signaling. The cytoplasmic kinase BIK1 acts downstream of …

BBX21, an Arabidopsis B-box protein, directly activates HY5 and is targeted by COP1 for 26S proteasome-mediated degradation

D Xu, Y Jiang, J Li, F Lin, M Holm… - Proceedings of the …, 2016 - National Acad Sciences
BBX21 (also known as SALT TOLERANCE HOMOLOG 2), a B-box (BBX)-containing protein,
has been previously identified as a positive regulator of light signaling; however, the precise …

COP1 and BBXs‐HY5‐mediated light signal transduction in plants

D Xu - New Phytologist, 2020 - Wiley Online Library
Light is one of the most essential environmental factors affecting many aspects of growth
and developmental processes in plants. Plants undergo skotomorphogenic or …

Illuminating the COP1/SPA ubiquitin ligase: fresh insights into its structure and functions during plant photomorphogenesis

J Ponnu, U Hoecker - Frontiers in Plant Science, 2021 - frontiersin.org
CONSTITUTIVE PHOTOMORPHOGENIC 1 functions as an E3 ubiquitin ligase in plants and
animals. Discovered originally in Arabidopsis thaliana, COP1 acts in a complex with SPA …

The lowdown on breakdown: Open questions in plant proteolysis

NA Eckardt, T Avin-Wittenberg, DC Bassham… - The Plant …, 2024 - academic.oup.com
Proteolysis, including post-translational proteolytic processing as well as protein
degradation and amino acid recycling, is an essential component of the growth and …

An Arabidopsis SUMO E3 ligase, SIZ1, negatively regulates photomorphogenesis by promoting COP1 activity

XL Lin, D Niu, ZL Hu, DH Kim, YH Jin, B Cai, P Liu… - PLoS …, 2016 - journals.plos.org
COP1 (CONSTITUTIVE PHOTOMORPHOGENIC 1), a ubiquitin E3 ligase, is a central
negative regulator of photomorphogenesis. However, how COP1 activity is regulated by post …

The B-box domain protein BBX21 promotes photomorphogenesis

D Xu, Y Jiang, J Li, M Holm, XW Deng - Plant Physiology, 2018 - academic.oup.com
Abstract B-box-containing (BBX) proteins play critical roles in a variety of cellular and
developmental processes in plants. BBX21 (also known as SALT TOLERANCE …