Huntington's disease is a progressive, fatal, neurodegenerative disorder caused by an
expanded CAG repeat in the huntingtin gene, which encodes an abnormally long …

Huntington's disease (HD) is a progressive, fatal neurological condition caused by an
expansion of CAG (glutamine) repeats in the coding region of the Huntington gene. To date …

Huntington's disease (HD) pathology is well understood at a histological level but a
comprehensive molecular analysis of the effect of the disease in the human brain has not …

Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by
a triplet (CAG) expansion mutation. The length of the triplet repeat is the most important …

Huntington's disease (HD) is characterized by the accumulation of a pathogenic protein,
Huntingtin (Htt), that contains an abnormal polyglutamine expansion. Here, we report that a …

Huntington's disease (HD) is caused by an expansion of cytosine–adenine–guanine (CAG)
repeats in the huntingtin gene, which leads to neuronal loss in the striatum and cortex and to …

Huntington's disease (HD) is caused by polyglutamine expansion (exp) in huntingtin (Htt).
The type 1 inositol (1, 4, 5)-triphosphate receptor (InsP 3 R1) is an intracellular calcium (Ca …

We present evidence for a specific role of p53 in the mitochondria-associated cellular
dysfunction and behavioral abnormalities of Huntington's disease (HD). Mutant huntingtin …

Previous work suggests N-methyl-D-aspartate receptor (NMDAR) activation may be involved
in degeneration of medium-sized spiny striatal neurons in Huntington's disease (HD). Here …

Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder caused by
expansion of CAG triplet repeats in the huntingtin (HTT) gene (also called HD) and …