Abstract In 2003 Rubenstein and Merzenich hypothesized that some forms of Autism (ASD)
might be caused by a reduction in signal-to-noise in key neural circuits, which could be the …

Highlights•Synaptic scaling and BCM models predict similar changes in synaptic strength.•In
vivo data suggest synaptic scaling and BCM to occur simultaneously and to …

Brain circuits process information through specialized neuronal subclasses interacting
within a network. Revealing their interplay requires activating specific cells while monitoring …

Synaptic scaling is a key homeostatic plasticity mechanism and is thought to be involved in
the regulation of cortical activity levels. Here we investigated the spatial scale of homeostatic …

Major depression is a complex and severe psychiatric disorder whose symptomatology
encompasses a critical shift in awareness, especially in the balance from external to internal …

Inhibitory interneurons comprise only about 20% of cortical neurons and thus constitute a
clear minority compared to the vast number of excitatory projection neurons. They are …

Mice lacking the Dlx1 and Dlx2 homeobox genes (Dlx1/2 mutants) have severe deficits in
subpallial differentiation, including overexpression of the Gsx1 and Gsx2 homeobox genes …

The effects of normal aging on morphologic and electrophysiologic properties of layer 3
pyramidal neurons in rhesus monkey primary visual cortex (V1) were assessed with whole …

Chronic changes in excitability and activity can induce homeostatic plasticity. These
perturbations may be associated with neurological disorders, particularly those involving …

Abstract Alpha rhythms (9–11 Hz) are a dominant feature of EEG recordings, particularly
over occipital cortex on cessation of a visual stimulation. Little is known about underlying …