Telomere dysfunction in ageing and age-related diseases

F Rossiello, D Jurk, JF Passos… - Nature cell …, 2022 - nature.com
Ageing organisms accumulate senescent cells that are thought to contribute to body
dysfunction. Telomere shortening and damage are recognized causes of cellular …

Global epidemiology of dyslipidaemias

A Pirillo, M Casula, E Olmastroni, GD Norata… - Nature Reviews …, 2021 - nature.com
Dyslipidaemias are alterations to the plasma lipid profile that are often associated with
clinical conditions. Dyslipidaemias, particularly elevated plasma LDL-cholesterol levels, are …

[PDF][PDF] Global epidemiology of ischemic heart disease: results from the global burden of disease study

MAB Khan, MJ Hashim, H Mustafa, MY Baniyas… - Cureus, 2020 - cureus.com
Background Ischemic heart disease (IHD) is a leading cause of death worldwide. Also
referred to as coronary artery disease (CAD) and atherosclerotic cardiovascular disease …

Vascular smooth muscle cells in atherosclerosis: time for a re-assessment

MOJ Grootaert, MR Bennett - Cardiovascular research, 2021 - academic.oup.com
Vascular smooth muscle cells (VSMCs) are key participants in both early and late-stage
atherosclerosis. VSMCs invade the early atherosclerotic lesion from the media, expanding …

[HTML][HTML] Physical activity, exercise, and chronic diseases: A brief review

E Anderson, JL Durstine - Sports medicine and health science, 2019 - Elsevier
Chronic diseases are the leading cause of death worldwide with increasing prevalence in all
age groups, genders, and ethnicities. Most chronic disease deaths occur in middle-to low …

CAPTURE: a multinational, cross-sectional study of cardiovascular disease prevalence in adults with type 2 diabetes across 13 countries

O Mosenzon, A Alguwaihes, JLA Leon… - Cardiovascular …, 2021 - Springer
Background There is a paucity of global data on cardiovascular disease (CVD) prevalence
in people with type 2 diabetes (T2D). The primary objective of the CAPTURE study was to …

Triglyceride–glucose index and the incidence of atherosclerotic cardiovascular diseases: a meta-analysis of cohort studies

X Ding, X Wang, J Wu, M Zhang, M Cui - Cardiovascular Diabetology, 2021 - Springer
Background Insulin resistance has been demonstrated to be involved in the pathogenesis of
atherosclerotic cardiovascular diseases (ASCVDs). This study evaluated the association …

RNA interference targeting ANGPTL3 for triglyceride and cholesterol lowering: phase 1 basket trial cohorts

GF Watts, C Schwabe, R Scott, PA Gladding… - Nature Medicine, 2023 - nature.com
Elevated triglycerides and non-high-density lipoprotein cholesterol (HDL-C) are risk factors
for atherosclerotic cardiovascular disease (ASCVD). ARO-ANG3 is an RNA interference …

Seaweed production: overview of the global state of exploitation, farming and emerging research activity

AH Buschmann, C Camus, J Infante… - European Journal of …, 2017 - Taylor & Francis
The use of seaweeds has a long history, as does the cultivation of a select and relatively
small group of species. This review presents several aspects of seaweed production, such …

[HTML][HTML] GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential

X Ma, Z Liu, I Ilyas, PJ Little, D Kamato… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Type 2 diabetes mellitus (T2DM) is closely associated with cardiovascular diseases (CVD),
including atherosclerosis, hypertension and heart failure. Some anti-diabetic medications …