[HTML][HTML] Pharmaceutical cocrystals: A review of preparations, physicochemical properties and applications

M Guo, X Sun, J Chen, T Cai - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Pharmaceutical cocrystals are multicomponent systems in which at least one component is
an active pharmaceutical ingredient and the others are pharmaceutically acceptable …

Towards medicinal mechanochemistry: evolution of milling from pharmaceutical solid form screening to the synthesis of active pharmaceutical ingredients (APIs)

D Tan, L Loots, T Friščić - Chemical Communications, 2016 - pubs.rsc.org
This overview highlights the emergent area of mechanochemical reactions for making active
pharmaceutical ingredients (APIs), and covers the latest advances in the recently …

Molecular crystalline materials with tunable luminescent properties: from polymorphs to multi-component solids

D Yan, DG Evans - Materials Horizons, 2014 - pubs.rsc.org
Tuning and controlling the luminescent properties of molecular materials by changing the
orientation and arrangement of the fluorophores within a solid has played an important role …

Real-time and in situ monitoring of mechanochemical reactions: A new playground for all chemists

K Uzarevic, I Halasz, T Friscic - The journal of physical chemistry …, 2015 - ACS Publications
We provide a brief overview of the first techniques for direct, real-time observation of
mechanochemical reactions by milling. Whereas mechanisms and kinetics of solid-state …

Two‐component molecular materials of 2, 5‐diphenyloxazole exhibiting tunable ultraviolet/blue polarized emission, pump‐enhanced luminescence, and …

D Yan, H Yang, Q Meng, H Lin… - Advanced Functional …, 2014 - Wiley Online Library
The development of π‐conjugated molecular systems with high‐efficiency generation of UV
and blue light plays an important role in the fields of light‐emitting diodes, fluorescent …

Accelerated ageing reactions: towards simpler, solvent-free, low energy chemistry

I Huskić, CB Lennox, T Friščić - Green Chemistry, 2020 - pubs.rsc.org
We provide an overview of chemical transformations that proceed spontaneously, by mixing
of initially solid reactants, and are accelerated and/or directed through gentle stimuli in the …

Introductory Lecture: Mechanochemistry, a versatile synthesis strategy for new materials

W Jones, MD Eddleston - Faraday discussions, 2014 - pubs.rsc.org
Mechanochemistry deals with reactions induced by the input of mechanical energy–for
example by impacts within a vibratory ball mill. The technique has a long history with …

Cocrystals of carbamazepine: Structure, mechanical properties, fluorescence properties, solubility, and dissolution rate

J Ouyang, L Liu, Y Li, M Chen, L Zhou, Z Liu, L Xu… - Particuology, 2024 - Elsevier
Carbamazepine (CBZ) is an anticonvulsant with very low water solubility, presenting as a
white crystalline powder with poor mechanical properties and is hard to bend. To enhance …

Facile engineering of indomethacin-induced paclitaxel nanocrystal aggregates as carrier-free nanomedicine with improved synergetic antitumor activity

C Zhang, L Long, Y Xiong, C Wang… - … applied materials & …, 2019 - ACS Publications
Carrier-free nanomedicines mainly composed of drug nanocrystals are considered as
promising candidates for next-generation nanodrug formulations. However, such …

Strategy to enhance solid-state fluorescence and aggregation-induced emission enhancement effect in pyrimidine boron complexes

Y Kubota, K Kasatani, H Takai, K Funabiki… - Dalton …, 2015 - pubs.rsc.org
The synthesis and the solution/solid-state fluorescence properties of pyrimidine-based
monoboron complexes differing in terms of the substituents [either two fluorine atoms (BF2 …