Analyzing adverse drug reaction using statistical and machine learning methods: A systematic review

HR Kim, MD Sung, JA Park, K Jeong, HH Kim, S Lee… - Medicine, 2022 - journals.lww.com
Background: Adverse drug reactions (ADRs) are unintended negative drug-induced
responses. Determining the association between drugs and ADRs is crucial, and several …

Use of electronic health record data for drug safety signal identification: a scoping review

SE Davis, L Zabotka, RJ Desai, SV Wang, JC Maro… - Drug Safety, 2023 - Springer
Introduction Pharmacovigilance programs protect patient health and safety by identifying
adverse event signals through postmarketing surveillance of claims data and spontaneous …

Propensity score‐adjusted three‐component mixture model for drug‐drug interaction data mining in FDA Adverse Event Reporting System

X Wang, L Li, L Wang, W Feng, P Zhang - Statistics in Medicine, 2020 - Wiley Online Library
With increasing trend of polypharmacy, drug‐drug interaction (DDI)‐induced adverse drug
events (ADEs) are considered as a major challenge for clinical practice. As premarketing …

Drug-drug interaction prediction based on co-medication patterns and graph matching

WH Chiang, L Shen, L Li… - International Journal of …, 2020 - inderscienceonline.com
High-order drug-drug interactions (DDIs) and associated adverse drug reactions (ADRs) are
common, particularly for elderly people, and therefore represent a significant public health …

Deep learning for high-order drug-drug interaction prediction

B Peng, X Ning - Proceedings of the 10th ACM international conference …, 2019 - dl.acm.org
Drug-drug interactions (DDIs) and their associated adverse drug reactions (ADRs) represent
a significant detriment to the public health. Existing research on DDIs is primarily focused on …

Application of an Innovative Data Mining Approach Towards Safe Polypharmacy Practice in Older Adults

Y Shi, CW Chiang, KT Unroe, X Oyarzun-Gonzalez… - Drug Safety, 2024 - Springer
Introduction Polypharmacy is common and is associated with higher risk of adverse drug
event (ADE) among older adults. Knowledge on the ADE risk level of exposure to different …

Random control selection for conducting high‐throughput adverse drug events screening using large‐scale longitudinal health data

CW Chiang, P Zhang, M Donneyong… - CPT …, 2021 - Wiley Online Library
Case‐control design based high‐throughput pharmacoinformatics study using large‐scale
longitudinal health data is able to detect new adverse drug event (ADEs) signals. Existing …

A super‐combo‐drug test to detect adverse drug events and drug interactions from electronic health records in the era of polypharmacy

A Zhu, D Zeng, L Shen, X Ning, L Li… - Statistics in …, 2020 - Wiley Online Library
Pharmacoinformatics research has experienced a great deal of successes in detecting drug‐
induced adverse events (AEs) using large‐scale health record databases. In the era of …

Pattern discovery from high-order drug-drug interaction relations

WH Chiang, T Schleyer, L Shen, L Li, X Ning - Journal of Healthcare …, 2018 - Springer
Drug-drug interactions (DDIs) and associated adverse drug reactions (ADRs) represent a
significant public health problem in the USA. The research presented in this manuscript …

[PDF][PDF] Analiza faktora rizika za nastanak nepoželjnih interakcija lekova kod pacijenata u neurološkoj jedinici intenzivne nege

D Aleksić - Универзитет у Крагујевцу, 2020 - nardus.mpn.gov.rs
САЖЕТАК Увод: Клинички релевантне потенцијалне интеракције лекова (ПИЛ)
сматрају се нежељеним реакцијама на лек које се могу спречити. Циљ ове дисертације …