We have systematically reviewed the presence, functional responses and regulation of α1‐,
α2‐and β‐adrenoceptors in the bladder, urethra and prostate, with special emphasis on …

In both ageing men and women, lower urinary tract symptoms (LUTS) are increasing. These
infections have many possible causes, including smooth muscle dysfunction, neurological …

The identification of the fundamental role of apoptosis in the growth balance and normal
homeostasis against cell proliferation led to the recognition of its loss contributing to …

Purpose: We tested the effects of a saw palmetto herbal blend in men with symptomatic
benign prostatic hyperplasia (BPH) via a randomized, placebo controlled trial. Materials and …

Recent evidence from our laboratory has demonstrated thatα1-adrenoceptor antagonists
doxazosin and terazosin induced apoptosis in prostate epithelial and smooth muscle cells in …

PURPOSE: Doxazosin and terazosin are known to relax prostate smooth muscle through
blockade of α1-adrenergic innervation to the prostate. This action alone however does not …

Recent evidence suggests that the quinazoline-based α1-adrenoceptor antagonists,
doxazosin and terazosin, exhibit a potent apoptotic effect against prostate tumor epithelial …

Purpose: To determine the expression and localization of the alpha1A-1, alpha1B and
alpha1D-adrenoceptor (AR) subtypes in hyperplastic and non-hyperplastic human prostate …

Purpose: Recent evidence indicated that an alpha1 blocker, doxazosin, induces prostate
apoptosis in patients with benign prostatic hyperplasia (BPH). in this study, to determine …

Recent studies have shown that the prostatic autonomic innervation takes part in its
homeostasis and growth. Other works showed that spontaneously hypertensive rats (SHR) …