Cell volume regulation is a basic homeostatic mechanism transcendental for the normal
physiology and function of cells. It is mediated principally by the activation of osmolyte …

The CNS is particularly vulnerable to reductions in plasma osmolarity, such as occur during
hyponatremia, the most commonly encountered electrolyte disorder in clinical practice. In …

Thrombin has been detected and demonstrated to play a role in the airways of patients with
bronchial asthma, but its role in the upper airways including during allergic rhinitis is …

The involvement of WNK3 (with no lysine [K] kinase) in cell volume regulation evoked by
anisotonic conditions was investigated in two modified stable lines of HEK293 cells: WNK3+ …

Cell volume is determined genetically for each cell lineage, but it is not a static feature of the
cell. Intracellular volume is continuously challenged by metabolic reactions, uptake of …

Abstract Aims The ClC-3 chloride channel (and current, I Cl, ClC-3) plays an important role
in cell volume regulation, proliferation, and apoptosis in vascular smooth muscle cells, and …

Volume-sensitive outwardly rectifying (VSOR) Cl− channels are critical for the regulatory
volume decrease (RVD) response triggered upon cell swelling. Recent evidence indicates …

Background/Aims: Neural stem/progenitor cells (NPCs) endure important changes in cell
volume during growth, proliferation and migration. As a first approach to know about NPC …

Background: ICln is a multifunctional protein involved in the generation of chloride currents
activated during regulatory volume decrease (RVD) after cell swelling (IClswell). Growth …

Activation of protein-activated receptor (PAR-1) by thrombin potentiates the hyposmotic
efflux of 3 Hd-aspartate and 3 H-taurine from cultured cerebellar astrocytes. This effect is …