The neuroprotective effect of MicroRNA‐22‐3p modified tetrahedral framework nucleic acids on damaged retinal neurons via TrkB/BDNF signaling pathway
J Li, L Xiao, N Yan, Y Li, Y Wang, X Qin… - Advanced Functional …, 2021 - Wiley Online Library
Glaucoma is the world's leading irreversible cause of blindness. It is characterized by
progressive retinal ganglion cells (RGCs) loss and axon damage, and there is no effective …
progressive retinal ganglion cells (RGCs) loss and axon damage, and there is no effective …
Novel lawsone-containing ruthenium (II) complexes: Synthesis, characterization and anticancer activity on 2D and 3D spheroid models of prostate cancer cells
RA De Grandis, PWS Dos Santos, KM de Oliveira… - Bioorganic …, 2019 - Elsevier
This study describes a series of newly synthesized phosphine/diimine ruthenium complexes
containing the lawsone as bioligand with enhanced cytotoxicity against different cancer …
containing the lawsone as bioligand with enhanced cytotoxicity against different cancer …
Ru (II)/amino acid complexes inhibit the progression of breast cancer cells through multiple mechanism-induced apoptosis
F Mello-Andrade, APM Guedes, WC Pires… - Journal of Inorganic …, 2022 - Elsevier
For some cancer subtypes, such as triple-negative breast cancer, there are no specific
therapies, which leads to a poor prognosis associated with invasion and metastases …
therapies, which leads to a poor prognosis associated with invasion and metastases …
Ruthenium (II) diphosphine complexes with mercapto ligands that inhibit topoisomerase IB and suppress tumor growth in vivo
MM da Silva, GH Ribeiro, MS de Camargo… - Inorganic …, 2021 - ACS Publications
Ruthenium (II) complexes (Ru1–Ru5), with the general formula [Ru (NS)(dppe) 2] PF6,
bearing two 1, 2-bis (diphenylphosphino) ethane (dppe) ligands and a series of mercapto …
bearing two 1, 2-bis (diphenylphosphino) ethane (dppe) ligands and a series of mercapto …
Ruthenium (II) phosphine/mercapto complexes: their in vitro cytotoxicity evaluation and actions as inhibitors of topoisomerase and proteasome acting as possible …
GH Ribeiro, APM Guedes, TD de Oliveira… - Inorganic …, 2020 - ACS Publications
In this paper, a series of new ruthenium complexes of the general formula [Ru
(NS)(dpphpy)(dppb)] PF6 (Ru1–Ru3), where dpphpy= diphenyl-2-pyridylphosphine, NS …
(NS)(dpphpy)(dppb)] PF6 (Ru1–Ru3), where dpphpy= diphenyl-2-pyridylphosphine, NS …
In vitro cytotoxicity and in vivo zebrafish toxicity evaluation of Ru (ii)/2-mercaptopyrimidine complexes
VS Velozo-Sá, LR Pereira, AP Lima… - Dalton …, 2019 - pubs.rsc.org
In this paper, four new ruthenium complexes,[Ru (N–S)(dppm) 2] PF6 (1),[Ru (N–S)(dppe) 2]
PF6 (2),[Ru (N–S) 2 (dppp)](3) and [Ru (N–S) 2 (PPh3) 2](4)[dppm= 1, 1-bis …
PF6 (2),[Ru (N–S) 2 (dppp)](3) and [Ru (N–S) 2 (PPh3) 2](4)[dppm= 1, 1-bis …
Ruthenium(II)/Benzonitrile Complex Induces Cytotoxic Effect in Sarcoma-180 Cells by Caspase-Mediated and Tp53/p21-Mediated Apoptosis, with Moderate Brine …
RS Faria, HD Silva, F Mello-Andrade, WC Pires… - … Trace Element Research, 2020 - Springer
Ruthenium (II)/benzonitrile complexes have demonstrated promising anticancer properties.
Considering that there are no specific therapies for treating sarcoma, we decided to evaluate …
Considering that there are no specific therapies for treating sarcoma, we decided to evaluate …
Ruthenium (II)/allopurinol complex inhibits breast cancer progression via multiple targets
IO Travassos, F Mello-Andrade, RP Caldeira… - JBIC Journal of …, 2021 - Springer
Metal complexes based on ruthenium have established excellent activity with less toxicity
and great selectivity for tumor cells. This study aims to assess the anticancer potential of …
and great selectivity for tumor cells. This study aims to assess the anticancer potential of …
基于JAK2/STAT3 信号通路探讨白藜芦醇对骨肉瘤MG-63 细胞凋亡及迁移的影响.
李家驹， 刘振辉， 孙天宇， 姬昌彬… - Progress in Modern …, 2022 - search.ebscohost.com
摘要目的: 研究白藜芦醇(RES) 通过蛋白酪氨酸激酶2/信号转导子与激活子3 (JAK2/STAT3)
信号通路对人骨肉瘤体外细胞株MG-63 细胞凋亡, 侵袭和迁移的影响. 方法: 体外培养MG-63 …
信号通路对人骨肉瘤体外细胞株MG-63 细胞凋亡, 侵袭和迁移的影响. 方法: 体外培养MG-63 …
Ru (II)-Based Amino Acid Complexes Show Promise for Leukemia Treatment: Cytotoxicity and Some Light on their Mechanism of Action
AP de Lima, MAP Almeida, F Mello-Andrade… - Biological trace element …, 2020 - Springer
Ruthenium is attracting considerable interest as the basis for new compounds to treat
diseases, and studies have shown that complexes with different structures have significant …
diseases, and studies have shown that complexes with different structures have significant …