Chromobacterium is a rod-shaped, Gram-negative, facultatively anaerobic bacteria with a
cosmopolitan distribution. Just about 160 Chromobacterium violaceum incidents have been …

Activating inflammatory caspases and releasing pro-inflammatory mediators are two
essential functions of inflammasomes which are triggered in response to pathogen …

Interferons (IFNs) induce an antimicrobial state, protecting tissues from infection. Many
viruses inhibit IFN signaling, but whether bacterial pathogens evade IFN responses remains …

Abstract The caspase-4/11-GSDMD pyroptosis axis recognizes cytosolic lipopolysaccharide
for antibacterial defenses. Shigella flexneri employs an OspC3 effector to block pyroptosis …

Granulomas often form around pathogens that cause chronic infections. Here, we discover
an innate granuloma model in mice with an environmental bacterium called …

Multiple eukaryotic cell processes are modulated by calcium ions (Ca 2+). As such, Ca 2+ is
emerging as a crucial regulator of innate immunity in multicellular organisms. In particular …

Pyroptosis is a proinflammatory form of programmed cell death featured with membrane
pore formation that causes cellular swelling and allows the release of intracellular …

The intracellular bacterial pathogen Legionella pneumophila utilizes the Dot/Icm system to
translocate over 330 effectors into the host cytosol. These virulence factors modify a variety …

Abstract Ethnopharmacological relevance The Mongolian medicine Eerdun Wurile is a
commonly used Mongolian in folk medicine used to treat cerebral nervous system diseases …

Calcium signaling is a cornerstone of plant defense responses. In this opinion article we
explore how pathogens exploit this pathway by targeting calcium sensors such as …