A hybrid mechanistic-empirical model for in silico mammalian cell bioprocess simulation
In cell culture processes cell growth and metabolism drive changes in the chemical
environment of the culture. These environmental changes elicit reactor control actions, cell …
environment of the culture. These environmental changes elicit reactor control actions, cell …
[PDF][PDF] Enhanced understanding of protein glycosylation in CHO cells through computational tools and experimentation
P Kotidis - 2021 - core.ac.uk
Chinese hamster ovary (CHO) cells are the workhorse of the multibillion-dollar
biopharmaceuticals industry. They have been extensively harnessed for recombinant …
biopharmaceuticals industry. They have been extensively harnessed for recombinant …
Advancing Cell Culture Engineering Through Mechanistic Model Optimization
CM O'Brien - 2020 - search.proquest.com
Over the past few decades, the emergence of new classes of treatments, including protein
therapeutics, gene therapies, and cell therapies, has ushered in a new era of medicine …
therapeutics, gene therapies, and cell therapies, has ushered in a new era of medicine …