Cold-stored platelets: A product with function optimized for hemorrhage control

KM Reddoch-Cardenas, JA Bynum… - … and Apheresis Science, 2019 - Elsevier
Early administration of blood products following severe trauma is pivotal for establishing
hemostasis and achieving successful outcomes. Platelet transfusions, in particular, provide …

Cold-stored platelets for acute bleeding in cardiac surgical patients: a narrative review

J Lu, K Karkouti, M Peer, M Englesakis… - Canadian Journal of …, 2023 - Springer
Purpose Cold-stored platelets (CSP) are an increasingly active topic of international
research. They are maintained at 1–6° C, in contrast to standard room-temperature platelets …

[PDF][PDF] 血小板及其衍生物的保存方案和应用进展

潘宗岱, 薛静, 孙士鹏, 刘贵建, 苗翠华… - 临床血液学杂志, 2022 - lcxy.whuhzzs.com
血小板不仅在止血, 凝血中起着重要作用, 而且随着研究的深入发现血小板的成分和衍生物还
可以应用于疾病的诊断和治疗, 在医美方面也有着广泛的应用. 随着血小板研究价值的升高 …

Transition from room temperature to cold‐stored platelets for the preservation of blood inventories during the COVID‐19 pandemic

MA Warner, EB Kurian, SA Hammel… - …, 2021 - Wiley Online Library
Background The COVID‐19 pandemic has placed great strain on blood resources. In an
effort to extend platelet (PLT) shelf life and minimize waste, our institution transitioned room …

A comparison of platelet function in cold‐stored whole blood and platelet concentrates

S Huish, L Green, C Kempster, P Smethurst… - …, 2021 - Wiley Online Library
Background There is renewed interest in the use of whole blood (WB) for the resuscitation of
trauma patients. Platelet function in stored WB compared to platelet concentrates is not well …

In vitro quality and platelet function of cold and delayed cold storage of apheresis platelet concentrates in platelet additive solution for 21 days

H Braathen, J Sivertsen, THF Lunde… - …, 2019 - Wiley Online Library
BACKGROUND Cold storage of platelets may extend shelf life compared to room
temperature storage. This study aimed to investigate in vitro platelet quality and function in …

Expanding the platelet inventory to mitigate the impact of severe shortages

JR Stubbs, BH Shaz, RR Vassallo, JD Roback - Hematology, 2022 - ashpublications.org
The platelet collection and distribution system, based on volunteer nonremunerated donors,
apheresis platelet collections, and primarily 1-directional distribution of platelets for up to 5 …

Frozen and cold-stored platelets: reconsidered platelet products

T Jimenez-Marco, A Castrillo, F Hierro-Riu, V Vicente… - Platelets, 2022 - Taylor & Francis
Platelet transfusion, both prophylactic and therapeutic, is a key element in modern medicine.
Currently, the standard platelet product for clinical use is platelet concentrates at room …

Implementation of a dual platelet inventory in a tertiary hospital during the COVID‐19 pandemic enabling cold‐stored apheresis platelets for treatment of actively …

H Braathen, KG Hagen, EK Kristoffersen… - …, 2022 - Wiley Online Library
Background To increase preparedness and mitigate the risk of platelet shortage without
increasing the number of collections, we introduced a dual platelet inventory with cold …

Extended storage of thawed platelets: refrigeration supports postthaw quality for 10 days

L Johnson, S Vekariya, S Tan, MP Padula… - Transfusion, 2020 - Wiley Online Library
Background Cryopreservation of platelets with dimethylsulfoxide (DMSO) at− 80° C
increases their shelf life from days to years. Once thawed, platelets are stored at room …