The use of derivatives of natural and synthetic origin has gained attention because of their
therapeutic effects against human diseases. Coumarins are one of the most common …

The progress in the field of cytotoxic compounds based on coumarin–pyrazoline hybrids is
presented in this literature review. Most of these hybrids have been obtained via ring closure …

A new series of 7-substituted coumarin scaffolds containing a methyl ester moiety at the C4-
position were synthesized and tested for their in vitro anti-proliferative activity against MCF-7 …

In the present study, the design and synthesis of novel coumarin derivatives 8a-h, 11a-d and
16a-c as potential selective inhibitors for the tumor associated human carbonic anhydrase …

A novel series of coumarin–pyrazoline hybrids 3a–f, 4a–c and 5a–c have been synthesized
and tested for their antiproliferative activity against the breast cancer cell line MCF-7. The …

We synthesized a new series of coumarin-piperazine 1, 2, 3-triazole hybrids (7a–7n) and
screened for their in vitro anti-breast cancer activity against MCF-7, MDA-MB-468, and MDA …

Globally, breast cancer (BC) has the highest prevalence among malignant diseases. BC is
also the primary cause of death among women. Notably, BC morbidity has been increasing …

In the current study, unique series of coumarin sulfonate and sulfamate derivatives were
synthesized. Their selectivity and inhibitory activity against glaucoma and cancer-associated …

Herein, we synthesized some new hybrids (5 a–5 o) containing coumarine, thiazolidine‐2, 4‐
dione and pyrazole entities using earlier developed Knoevenagel condensation and tandem …

ABSTRACT A new series of 3-(5-Hydroxy-1-isonicotinoyl-3-methyl-4, 5-dihydro-1H-pyrazol-
5-yl)-2H-chromen-2-one derivatives 3a-g was efficiently synthesized under environmentally …