Butyrate: a bridge between intestinal flora and rheumatoid arthritis
Y Cao, J Chen, J Xiao, Y Hong, K Xu, Y Zhu - Frontiers in Immunology, 2024 - frontiersin.org
In patients with rheumatoid arthritis (RA), intestinal flora imbalance and butyrate metabolism
disorders precede clinical arthritis and are associated with the pathogenesis of RA. This …
disorders precede clinical arthritis and are associated with the pathogenesis of RA. This …
Insights into the complexities of Citrullination: From immune regulation to autoimmune disease
J Wang, J Miao, P Zhu - Autoimmunity Reviews, 2024 - Elsevier
Citrullination, a post-translational modification that changes arginine to citrulline in proteins,
is vital for immune response modulation and cell signaling. Catalyzed by peptidyl arginine …
is vital for immune response modulation and cell signaling. Catalyzed by peptidyl arginine …
Autoreactive B cells against malondialdehyde-induced protein cross-links are present in the joint, lung, and bone marrow of rheumatoid arthritis patients
P Sahlström, V Joshua, V Valkovskaia, C Biese… - Journal of Biological …, 2023 - ASBMB
Autoantibodies to malondialdehyde (MDA) proteins constitute a subset of anti-modified
protein autoantibodies in rheumatoid arthritis (RA), which is distinct from citrulline reactivity …
protein autoantibodies in rheumatoid arthritis (RA), which is distinct from citrulline reactivity …
The role of lactylation in plasma cells and its impact on rheumatoid arthritis pathogenesis: insights from single-cell RNA sequencing and machine learning
W Fu, T Wang, Y Lu, T Shi, Q Yang - Frontiers in Immunology, 2024 - frontiersin.org
Introduction Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by
persistent synovitis, systemic inflammation, and autoantibody production. This study aims to …
persistent synovitis, systemic inflammation, and autoantibody production. This study aims to …
The peculiar features, diversity and impact of citrulline-reactive autoantibodies
B Raposo, L Klareskog, WH Robinson… - Nature Reviews …, 2024 - nature.com
Since entering the stage 25 years ago as a highly specific serological biomarker for
rheumatoid arthritis, anti-citrullinated protein antibodies (ACPAs) have been a topic of …
rheumatoid arthritis, anti-citrullinated protein antibodies (ACPAs) have been a topic of …
[HTML][HTML] Macrophage activation and inflammatory priming by anti-MAA antibodies in rheumatoid arthritis
M Afonso, J Sun, K Sakuraba, A Cîrciumaru… - Clinical …, 2024 - Elsevier
We studied the effects of rheumatoid arthritis (RA) autoantibodies that target
malondialdehyde-acetaldehyde protein adducts (anti-MAA) on inflammation and …
malondialdehyde-acetaldehyde protein adducts (anti-MAA) on inflammation and …
[HTML][HTML] Plasma TNF-α Elevation in Biologic Naive Rheumatoid Arthritis Patients Belonging to a Population with New Mutations in TLR4 and CYP51A1 genes without …
E Mosavi, M Bandehpour… - … of Molecular and …, 2024 - pmc.ncbi.nlm.nih.gov
In a system biology-based study, we previously reported that IL-6 and IL6R-specific m-RNA
levels were elevated in leukocytes of patients with Rheumatoid arthritis (RA). Here, the …
levels were elevated in leukocytes of patients with Rheumatoid arthritis (RA). Here, the …