Near infrared (NIR) spectroscopy has been widely recognized as a powerful PAT tool for
monitoring blend uniformity in continuous manufacturing (CM) processes. However, the …

The feed frame is a force-feeding device used in the die filling process. The die filling
process is crucial within pharmaceutical manufacturing to guarantee the critical quality …

Abstract A Near Infrared (NIR) method was developed using a small benchtop feed frame
system to quantify Saccharin potency in a powder blend during continuous manufacturing …

In-line measurements of low dose blends in the feed frame of a tablet press were performed
for API concentration levels as low as 0.10% w/w. The proposed methodology utilizes the …

Near infrared (NIR) spectroscopy is a valuable analytical technique for monitoring chemical
composition of powder blends in continuous pharmaceutical processes. However, the …

Compact composite probes were identified as a priority to alleviate space constraints in
miniaturized unit operations and pharmaceutical manufacturing platforms. Therefore, in this …

Near-infrared (NIR) spectroscopy is a powerful process analytical tool for monitoring
chemical constituents in continuous pharmaceutical processes. However, the density …

The article examines existing methods for assessing the homogeneity of feed mixes in the
feed industry and agriculture. As an alternative to existing approaches, the authors offer a …

The influence of different tableting process parameters on lead-lag was studied by collecting
in-line near-infrared (NIR) spectra in the filling chamber of the tablet press feed frame and off …

The tablet diversion strategy, based on in-line near-infrared (NIR) tablet press feed frame
measurements, can be a key component of both batch and continuous oral solid dose …