Chalcone scaffolds, bioprecursors of flavonoids: Chemistry, bioactivities, and pharmacokinetics

M Rudrapal, J Khan, AAB Dukhyil, RMII Alarousy… - Molecules, 2021 - mdpi.com
Chalcones are secondary metabolites belonging to the flavonoid (C6-C3-C6 system) family
that are ubiquitous in edible and medicinal plants, and they are bioprecursors of plant …

Chalcones: Synthetic chemistry follows where nature leads

HA Jasim, L Nahar, MA Jasim, SA Moore, KJ Ritchie… - Biomolecules, 2021 - mdpi.com
Chalcones belong to the flavonoid class of phenolic compounds. They form one of the
largest groups of bioactive natural products. The potential anticancer, anti-inflammatory …

Ethnobotanical survey of medicinal plant species used by communities around Mabira Central Forest Reserve, Uganda

P Tugume, EK Kakudidi, M Buyinza… - Journal of ethnobiology …, 2016 - Springer
Background An ethnobotanical study of medicinal plants was carried out in 14 villages
adjacent to Mabira Central Forest Reserve (CFR) in Central Uganda between August 2013 …

Naturally occurring chalcones and their biological activities

Z Rozmer, P Perjési - Phytochemistry reviews, 2016 - Springer
The aim of this review is to summarize the various naturally occurring chalcone compounds
which have been isolated from different plants. Chalcones considered as obligate …

A review of anti-infective and anti-inflammatory chalcones

Z Nowakowska - European journal of medicinal chemistry, 2007 - Elsevier
Chalcones, considered as the precursors of flavonoids and isoflavonoids, are abundant in
edible plants, and have also been shown to display a diverse array of pharmacological …

[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II

TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves… - 2012 - lavierebelle.org
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

Antimalarials from nature

K Kaur, M Jain, T Kaur, R Jain - Bioorganic & medicinal chemistry, 2009 - Elsevier
Malaria is a major public health problem mainly due to the development of resistance by the
most lethal causative parasitic species, Plasmodium falciparum to the mainstay drugs like …

Flavonoids and their glycosides, including anthocyanins

NC Veitch, RJ Grayer - Natural product reports, 2008 - pubs.rsc.org
Covering: January 2004 to December 2006. Previous review: Nat. Prod. Rep., 2004, 21, 539–
573 This review describes more than 600 new examples of naturally occurring flavonoids …

The potential of anti-malarial compounds derived from African medicinal plants, part II: a pharmacological evaluation of non-alkaloids and non-terpenoids

F Ntie-Kang, PA Onguéné, LL Lifongo, JC Ndom… - Malaria journal, 2014 - Springer
Malaria is currently a public health concern in many countries in the world due to various
factors which are not yet under check. Drug discovery projects targeting malaria often resort …

Naturally occurring prenylated chalcones from plants: Structural diversity, distribution, activities and biosynthesis

K Zhou, S Yang, SM Li - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to July 2020 Naturally occurring chalcones carrying up to three modified or
unmodified C5-, C10-, and C15-prenyl moieties on both rings A and B as well as at the α …