Recent research into the pathophysiology and treatment of atopic dermatitis (AD) has shown
notable progress. An increasing number of aspects of the immune system are being …

Mast cells are (in) famous for their role in allergic diseases, but the physiological and
pathophysiological roles of this ingenious cell are still not fully understood. Mast cells are …

Atopic dermatitis (AD) is one of the most prevalent inflammatory disease among non-fatal
skin diseases, affecting up to one fifth of the population in developed countries. AD is …

Interaction of mast cells (MCs) with fibroblasts is essential for MC maturation within tissue
microenvironments, although the underlying mechanism is incompletely understood …

Eosinophilic esophagitis (EoE) is a chronic, Th2-inflammatory disease of the esophagus that
can severely affect food intake. Currently, diagnosis and assessing response to treatment of …

Type 2 immune–mediated diseases give a clear answer to the issue of nature (genetics)
versus nurture (environment). Both genetics and environment play vital complementary roles …

abstract Mast cells (MCs) are derived from hematopoietic stem cells in the bone marrow, and
their maturation is regulated by the tissue environment, such as the skin, lung and gut …

Protein arginine methyltransferases (PRMTs) promote the methylation of numerous proteins
at their arginine residues. An increasing number of publications have suggested that …

Mast cells are major effector cells in eliciting allergic responses. They also play a significant
role in establishing innate and adaptive immune responses, as well as in modulating tumor …

This review highlights recent advances in the understanding of eosinophils and eosinophilic
diseases, particularly eosinophilic gastrointestinal diseases during the last year. The …