Nutrients, foods, and colorectal cancer prevention

M Song, WS Garrett, AT Chan - Gastroenterology, 2015 - Elsevier
Diet has an important role in the development of colorectal cancer. In the past few decades,
findings from extensive epidemiologic and experimental investigations have linked …

Meta-analyses of colorectal cancer risk factors

CM Johnson, C Wei, JE Ensor, DJ Smolenski… - Cancer causes & …, 2013 - Springer
Purpose Demographic, behavioral, and environmental factors have been associated with
increased risk of colorectal cancer (CRC). We reviewed the published evidence and …

Determining risk of colorectal cancer and starting age of screening based on lifestyle, environmental, and genetic factors

J Jeon, M Du, RE Schoen, M Hoffmeister, PA Newcomb… - Gastroenterology, 2018 - Elsevier
Background & Aims Guidelines for initiating colorectal cancer (CRC) screening are based
on family history but do not consider lifestyle, environmental, or genetic risk factors. We …

Endocrine-related adverse events following ipilimumab in patients with advanced melanoma: a comprehensive retrospective review from a single institution

M Ryder, M Callahan, MA Postow… - Endocrine-related …, 2014 - erc.bioscientifica.com
Novel immune checkpoint blockade with ipilimumab, an antibody blocking the cytotoxic T-
lymphocyte antigen 4 (CTLA4), is revolutionizing cancer therapy. However, ipilimumab …

Identification of genetic susceptibility loci for colorectal tumors in a genome-wide meta-analysis

U Peters, S Jiao, FR Schumacher, CM Hutter… - Gastroenterology, 2013 - Elsevier
BACKGROUND & AIMS: Heritable factors contribute to the development of colorectal
cancer. Identifying the genetic loci associated with colorectal tumor formation could …

Metabolism and biomarkers of heterocyclic aromatic amines in molecular epidemiology studies: lessons learned from aromatic amines

RJ Turesky, L Le Marchand - Chemical research in toxicology, 2011 - ACS Publications
Aromatic amines and heterocyclic aromatic amines (HAAs) are structurally related classes of
carcinogens that are formed during the combustion of tobacco or during the high …

Regression-based Deep-Learning predicts molecular biomarkers from pathology slides

OSM El Nahhas, CML Loeffler, ZI Carrero… - nature …, 2024 - nature.com
Deep Learning (DL) can predict biomarkers from cancer histopathology. Several clinically
approved applications use this technology. Most approaches, however, predict categorical …

[HTML][HTML] Tea polyphenols and their chemopreventive and therapeutic effects on colorectal cancer

ST Wang, WQ Cui, D Pan, M Jiang… - World journal of …, 2020 - ncbi.nlm.nih.gov
Colorectal cancer (CRC), a multifactorial disease, is usually induced and developed through
complex mechanisms, including impact of diet and lifestyle, genomic abnormalities, change …

Nongenetic determinants of risk for early-onset colorectal cancer

AN Archambault, Y Lin, J Jeon, TA Harrison… - JNCI cancer …, 2021 - academic.oup.com
Background Incidence of early-onset (younger than 50 years of age) colorectal cancer
(CRC) is increasing in many countries. Thus, elucidating the role of traditional CRC risk …

A model to determine colorectal cancer risk using common genetic susceptibility loci

L Hsu, J Jeon, H Brenner, SB Gruber, RE Schoen… - Gastroenterology, 2015 - Elsevier
Background & Aims Risk for colorectal cancer (CRC) can be greatly reduced through
screening. To aid in the development of screening strategies, we refined models designed to …