Retina in a dish: Cell cultures, retinal explants and animal models for common diseases of the retina

S Schnichels, F Paquet-Durand, M Löscher… - Progress in retinal and …, 2021 - Elsevier
For many retinal diseases, including age-related macular degeneration (AMD), glaucoma,
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …

Retinal toxicity of medical devices used during vitreoretinal surgery: a critical overview

K Januschowski, C Irigoyen, JC Pastor… - …, 2018 - karger.com
Retinal toxicity/biocompatibility of medical devices in direct contact with the retina is an
important subject for clinicians and scientists. As these effects are not very frequent, there is …

Retinal organ cultures as alternative research models

S Schnichels, T Kiebler, J Hurst… - Alternatives to …, 2019 - journals.sagepub.com
Ex vivo organ cultures represent unique research models, as they combine the advantages
of cell cultures with those of animal models. Being able to mimic in vivo situations through …

Extended law of corresponding states applied to solvent isotope effect on a globular protein

S Bucciarelli, N Mahmoudi, L Casal-Dujat… - The journal of …, 2016 - ACS Publications
Investigating proteins with techniques such as NMR or neutron scattering frequently requires
the partial or complete substitution of D2O for H2O as a solvent, often tacitly assuming that …

Analysis of retinal ganglion cell complex thickness after Brilliant Blue-assisted vitrectomy for idiopathic macular holes

MS Sevim, H Sanisoglu - Current Eye Research, 2013 - Taylor & Francis
Purpose: The purpose of this study was to evaluate retinal ganglion cell complex (GCC)
thickness changes in eyes undergoing Brilliant Blue-assisted macular hole surgery (MHS) …

Vital dyes in ophthalmology: a chemical perspective

E Badaro, EA Novais, FM Penha, M Maia… - Current eye …, 2014 - Taylor & Francis
Vital dyes have advanced diagnosis and surgical technique in various specialties, including
oncology, gastroenterology and ophthalmology. Intra-operative and diagnostic dyes are …

Heavy Water Reduces GFP Expression in Prokaryotic Cell‐Free Assays at the Translation Level While Stimulating Its Transcription

LS Hohlefelder, T Stögbauer, M Opitz… - BioMed research …, 2013 - Wiley Online Library
The in vitro proliferation of prokaryotic and eukaryotic cells is remarkably hampered in the
presence of heavy water (D2O). Impairment of gene expression at the transcription or …

Applications of deuterium oxide in human health

WC Bila, RMS Mariano, VR Silva… - … in Environmental and …, 2017 - Taylor & Francis
The main aim goal of this review was to gather information about recent publications related
to deuterium oxide (D2O), and its use as a scientific tool related to human health. Searches …

Vital dyes increase the rigidity of the internal limiting membrane

C Haritoglou, S Mauell, M Benoit, RG Schumann… - Eye, 2013 - nature.com
Purpose To assess the stiffness of the natural human internal limiting membrane (ILM) and
evaluate potential changes of the mechanical properties following staining with brilliant blue …

Glutamate and hypoxia as a stress model for the isolated perfused vertebrate retina

K Januschowski, S Müller, C Krupp, MS Spitzer… - JoVE (Journal of …, 2015 - jove.com
Neuroprotection has been a strong field of investigation in ophthalmological research in the
past decades and affects diseases such as glaucoma, retinal vascular occlusion, retinal …