Stress is an important risk factor for modern chronic diseases, with distinct influences in
males and females. The sex specificity of the mammalian stress response contributes to the …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) that affects about 2.5 million people worldwide. In MS, the patients' immune system …

Clinical observations indicate that activation of the TNF‐α system may contribute to the
development of inflammation‐associated depression. Here, we tested the hypothesis that …

The present study investigated the neuroprotective effect of taurine against the deleterious
effects of chronic‐recurrent neuroinflammation induced by LPS in the cerebellum of rats …

Calorie restriction (CR) has been shown to increase longevity and elicit many health
promoting benefits including delaying immunosenescence and attenuating …

Inflammatory reactions are involved in a diversity of diseases, including major depressive
disorder. Cytokines act as intercellular signaling molecules and mediators of inflammation …

Lipopolysaccharide (LPS) is used to induce inflammation and promotes nervous system
activation. Different regions of the brain present heterogeneous glial responses; thus, in …

Pain can be defined as an unpleasant sensory and emotional experience caused by either
actual or potential tissue damage or even resemble that unpleasant experience. For years …

Sickness behaviors have become the focus of great interest in recent years as they
represent a clear case of how peripheral disturbances in immune signaling can disrupt quite …

Aim Neuroinflammation is a critical pathogenic mechanism of most neurodegenerative
disorders especially, Alzheimer's disease (AD). Lipopolysaccharides (LPS) are known to …