Application and development trends of gas chromatography–ion mobility spectrometry for traditional Chinese medicine, clinical, food and environmental analysis

J Yin, M Wu, R Lin, X Li, H Ding, L Han, W Yang… - Microchemical …, 2021 - Elsevier
Abstract Rapid, non-destructive, accurate, and high-throughput screening of volatile
ingredients plays an important role in the field of analysis. Gas chromatography–ion mobility …

[HTML][HTML] Modern approaches for detection of volatile organic compounds in metabolic studies focusing on pathogenic bacteria: current state of the art

K Żuchowska, W Filipiak - Journal of Pharmaceutical Analysis, 2023 - Elsevier
Pathogenic microorganisms produce numerous metabolites, including volatile organic
compounds (VOCs). Monitoring these metabolites in biological matrices (eg, urine, blood, or …

Volatile organic compounds (VOCs) for the non-invasive detection of pancreatic cancer from urine

E Daulton, AN Wicaksono, A Tiele, HM Kocher… - Talanta, 2021 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is a particularly challenging cancer, with very
low 5-year survival rates. This low survival rate is linked to late stage diagnosis, associated …

Fecal volatile metabolomics predict gram-negative late-onset sepsis in preterm infants: a nationwide case-control study

NM Frerichs, S El Manouni El Hassani, N Deianova… - Microorganisms, 2023 - mdpi.com
Early detection of late-onset sepsis (LOS) in preterm infants is crucial since timely treatment
initiation is a key prognostic factor. We hypothesized that fecal volatile organic compounds …

Identification of volatile compounds from bacteria by spectrometric methods in medicine diagnostic and other areas: current state and perspectives

N Kunze-Szikszay, M Euler, T Perl - Applied Microbiology and …, 2021 - Springer
Diagnosis of bacterial infections until today mostly relies on conventional microbiological
methods. The resulting long turnaround times can lead to delayed initiation of adequate …

The detection of wound infection by ion mobility chemical analysis

E Daulton, A Wicaksono, J Bechar, JA Covington… - Biosensors, 2020 - mdpi.com
Surgical site infection represents a large burden of care in the National Health Service.
Current methods for diagnosis include a subjective clinical assessment and wound swab …

Prostate cancer screening using chemometric processing of GC–MS profiles obtained in the headspace above urine samples

V Deev, S Solovieva, E Andreev, V Protoshchak… - … of Chromatography B, 2020 - Elsevier
The development of screening methods for various types of cancer is of utmost importance
as the early diagnostics of these diseases significantly increases the chances for patient's …

GC–IMS facilitates identification of carbapenem-resistant Klebsiella pneumoniae in simulated blood cultures

F Li, Y Zheng, C Zhao, J Zhu, Y Hang, Y Fang, L Hu - AMB Express, 2024 - Springer
This study aimed to identify carbapenem-resistant Klebsiella pneumoniae (CRKP) based on
changes in levels of its volatile organic compounds (VOCs) in simulated blood cultures …

Screening of chorioamnionitis using volatile organic compound detection in exhaled breath: a Pre-clinical proof of concept study

DRMG Ophelders, AW Boots, MC Hütten… - Frontiers in …, 2021 - frontiersin.org
Chorioamnionitis is a major risk factor for preterm birth and an independent risk factor for
postnatal morbidity for which currently successful therapies are lacking. Emerging evidence …

Ion Mobility Spectrometry in Clinical and Emergency Setting: Research and Potential Applications

DM Ruszkiewicz, A Meister, R Myers - Breath Analysis: An Approach for …, 2022 - Springer
Interest in the use of GC-IMS for the detection of volatiles has seen a rapid expansion over
the last decade. The following chapter will focus on classical GC-IMS and its research …