During recent decades, nucleic acid aptamers have emerged as powerful biological
recognition elements for electrochemical affinity biosensors. These bioreceptors emulate or …

Aptamers are single-stranded nucleic acid sequences that can bind to target molecules with
high selectivity and affinity. Most aptamers are screened in vitro by a combinatorial biology …

In analogy to split-protein systems, which rely on the appropriate fragmentation of protein
domains, split aptamers made of two or more short nucleic acid strands have emerged as …

It has been almost 30 years since the invention of Systematic Evolution of Ligands by
Exponential Enrichment (SELEX) methodology and the description of the first aptamers. In …

In this study, the original chloramphenicol aptamer containing 80 bases was truncated to 30
bases with high affinity by the SYBR Green I assay. It was found that the ionic strength and …

Aptamers are nucleic acid-based affinity reagents that have been incorporated into a variety
of molecular sensor formats. However, many aptamer sensors exhibit insufficient sensitivity …

Transducers made from graphene-type materials are widely used in sensing applications.
However, utilization of graphene oxide obtained from electrochemical exfoliation of graphite …

Conventional directed evolution methods offer the ability to select bioreceptors with high
binding affinity for a specific target in terms of thermodynamic properties. However, there is a …

Nucleic-acid aptamers consisting in single-stranded DNA oligonucleotides emerged as very
promising biorecognition elements for electrochemical biosensors applied in various fields …

Colorimetric aptamer-based sensors offer a simple means of on-site or point-of-care analyte
detection. However, these sensors are largely incapable of achieving naked-eye detection …