Microscale thermophoresis as a powerful growing analytical technique for the investigation of biomolecular interaction and the determination of binding parameters

S El Deeb, A Al-Harrasi, A Khan… - … and Applications in …, 2022 - iopscience.iop.org
The in vitro panel of technologies to address biomolecular interactions are in play, however
microscale thermophoresis is continuously increasing in use to represent a key player in this …

Advanced mass spectrometric and spectroscopic methods coupled with machine learning for in vitro diagnosis

X Chen, W Shu, L Zhao, J Wan - View, 2023 - Wiley Online Library
In vitro diagnosis (IVD) is one vital component of medical tests that detects biological
samples of tissues or bio‐fluids. Recently, mass spectrometry and spectroscopy have been …

Mast cells as a target—A comprehensive review of recent therapeutic approaches

J Baran, A Sobiepanek, A Mazurkiewicz-Pisarek… - Cells, 2023 - mdpi.com
Mast cells (MCs) are the immune cells distributed throughout nearly all tissues, mainly in the
skin, near blood vessels and lymph vessels, nerves, lungs, and the intestines. Although MCs …

[HTML][HTML] The hidden potential of glycomarkers: Glycosylation studies in the service of cancer diagnosis and treatment

K Grzesik, M Janik, D Hoja-Łukowicz - Biochimica et Biophysica Acta (BBA) …, 2023 - Elsevier
Abstract Changes in the glycosylation process appear early in carcinogenesis and evolve
with the growth and spread of cancer. The correlation of the characteristic glycosylation …

[HTML][HTML] Discriminating bladder cancer cells through rheological mechanomarkers at cell and spheroid levels

K Gnanachandran, S Kędracka-Krok, J Pabijan… - Journal of …, 2022 - Elsevier
The stiffening or softening of cancers observed in nanoindentation experiments has been
recognized as a marker of cancer-related changes. In bladder cancers, continuous …

Microscale thermophoresis (MST) and Spectral Shift (SpS) in drug discovery

JS Nowak, A Czarna, P Grudnik, P Grygier… - TrAC Trends in …, 2024 - Elsevier
The techniques of Microscale Thermophoresis (MST), and recently introduced Spectral Shift
(SpS) have become valuable tools in target-based drug discovery owned to their ability of …

[HTML][HTML] Detecting normal and cancer skin cells via glycosylation and adhesion signatures: A path to enhanced microfluidic phenotyping

R Szydlak, M Luty, VE Prot, IH Øvreeide, J Zemła… - Biosensors and …, 2024 - Elsevier
Recruiting circulating cells based on interactions between surface receptors and
corresponding ligands holds promise for capturing cells with specific adhesive properties …

Fabrication of near infrared light responsive photoelectrochemical immunosensor for in vivo detection of melanoma cells

B Wang, CY Wei, KW Wang, B Fu, Y Chen… - Biosensors and …, 2023 - Elsevier
Effective and convenient detection of melanoma cells with high sensitivity is essential to
identify malignant melanoma in its early stage. However, the existing detection methods …

Anandamide-modulated changes in metabolism, glycosylation profile and migration of metastatic melanoma cells

A Sobiepanek, M Milner-Krawczyk, P Musolf, T Starecki… - Cancers, 2022 - mdpi.com
Simple Summary Anandamide (AEA) belongs to the group of endocannabinoids and
possesses various regulatory properties in physiological as well as pathological processes …

Thermophoretic Assay for Biosensing

H Ling, Y Yuan, F Chen, J Guo… - Advanced Materials …, 2024 - Wiley Online Library
Thermophoresis refers to the directional movement of particles driven by temperature
gradients, which is ubiquitous in nature. This phenomenon can be conveniently used to …