Macrophages are innate immune cells that form a 3D network in all our tissues, where they
phagocytose dying cells and cell debris, immune complexes, bacteria and other waste …

The high selectivity and affinity of antibodies toward their antigens have made them a highly
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …

The revolution in cancer immunotherapy over the last few decades has resulted in a
paradigm shift in the clinical care of cancer. Most of the cancer immunotherapeutic regimens …

Unconjugated monoclonal antibodies (mAbs) have revolutionized the treatment of many
types of cancer. Some of these mAbs promote the clearance of malignant cells via direct …

Redirection of tumor-associated macrophages to eliminate tumor cells holds great promise
for overcoming therapeutic resistance to rituximab and other antibody drugs. Here, we …

Successful immune responses depend on the spatiotemporal coordination of immune cell
migration, interactions, and effector functions in lymphoid and parenchymal tissues. Real …

Simple Summary Innate and adaptive immunity mutually regulate one another in a dynamic
fashion during immune responses. In infectious contexts, positive interactions between …

The major therapeutic goal for immune thrombocytopenic purpura (ITP) is to restore normal
platelet counts using drugs to promote platelet production or by interfering with mechanisms …

Macrophages are found in all tissues and display outstanding functional diversity. From
embryo to birth and throughout adult life, they play critical roles in development …

The clinical successes and tremendous hopes raised by tumor immunotherapies such as
tumor‐targeting monoclonal antibodies, immune checkpoint blockers, or CAR T cells …