Chronic kidney disease as a risk factor for heart failure with preserved ejection fraction: a focus on microcirculatory factors and therapeutic targets
J Van de Wouw, M Broekhuizen, O Sorop… - Frontiers in …, 2019 - frontiersin.org
Heart failure (HF) and chronic kidney disease (CKD) co-exist, and it is estimated that about
50% of HF patients suffer from CKD. Although studies have been performed on the …
50% of HF patients suffer from CKD. Although studies have been performed on the …
Direct and indirect effects of fibroblast growth factor 23 on the heart
T Nakano, H Kishimoto, M Tokumoto - Frontiers in endocrinology, 2023 - frontiersin.org
Fibroblast growth factor (FGF) 23 is a bone-derived phosphotropic hormone that regulates
phosphate and mineral homeostasis. Recent studies have provided evidence that a high …
phosphate and mineral homeostasis. Recent studies have provided evidence that a high …
Cardiac biomarkers and risk of incident heart failure in chronic kidney disease: the CRIC (Chronic Renal Insufficiency Cohort) Study
N Bansal, L Zelnick, A Go, A Anderson… - Journal of the …, 2019 - Am Heart Assoc
Background Cardiac biomarkers may signal mechanistic pathways involved in heart failure
(HF), a leading complication in chronic kidney disease. We tested the associations of NT …
(HF), a leading complication in chronic kidney disease. We tested the associations of NT …
Fibroblast growth factor 23—Klotho and hypertension: Experimental and clinical mechanisms
Hypertension (HTN) and chronic kidney disease (CKD) are increasingly recognized in
pediatric patients and represent risk factors for cardiovascular morbidity and mortality later in …
pediatric patients and represent risk factors for cardiovascular morbidity and mortality later in …
Change in cardiac biomarkers and risk of incident heart failure and atrial fibrillation in CKD: the Chronic Renal Insufficiency Cohort (CRIC) study
Rationale & Objective Circulating cardiac biomarkers may signal potential mechanistic
pathways involved in heart failure (HF) and atrial fibrillation (AF). Single measures of …
pathways involved in heart failure (HF) and atrial fibrillation (AF). Single measures of …
Vitamin D effects on bone homeostasis and cardiovascular system in patients with chronic kidney disease and renal transplant recipients
G Cianciolo, M Cappuccilli, F Tondolo, L Gasperoni… - Nutrients, 2021 - mdpi.com
Poor vitamin D status is common in patients with impaired renal function and represents one
main component of the complex scenario of chronic kidney disease–mineral and bone …
main component of the complex scenario of chronic kidney disease–mineral and bone …
Myocardial hypertrophy and fibrosis are associated with cardiomyocyte beta-catenin and TRPC6/Calcineurin/NFAT signaling in spontaneously hypertensive rats with …
E Bogdanova, O Beresneva, O Galkina… - International Journal of …, 2021 - mdpi.com
Background: Arterial hypertension (AH) is associated with heart and chronic kidney disease
(CKD). However, the precise mechanisms of myocardial remodeling (MR) in the settings of …
(CKD). However, the precise mechanisms of myocardial remodeling (MR) in the settings of …
Endocan and circulating progenitor cells in women with systemic sclerosis: association with inflammation and pulmonary hypertension
Background: Systemic sclerosis (SSc) is characterized by early vasculopathy and fibrosis in
the skin, lungs, and other tissues. Vascular manifestations of SSc include Raynaud's …
the skin, lungs, and other tissues. Vascular manifestations of SSc include Raynaud's …
Cardiac fibroblast growth factor 23 excess does not induce left ventricular hypertrophy in healthy mice
M Leifheit-Nestler, MA Wagner, B Richter… - Frontiers in cell and …, 2021 - frontiersin.org
Fibroblast growth factor (FGF) 23 is elevated in chronic kidney disease (CKD) to maintain
phosphate homeostasis. FGF23 is associated with left ventricular hypertrophy (LVH) in CKD …
phosphate homeostasis. FGF23 is associated with left ventricular hypertrophy (LVH) in CKD …
The intersection of mineralocorticoid receptor activation and the FGF23–Klotho cascade: a duopoly that promotes renal and cardiovascular injury
M Epstein, M Freundlich - Nephrology Dialysis Transplantation, 2022 - academic.oup.com
The nexus of chronic kidney disease (CKD) and cardiovascular disease (CVD) amplifies the
morbidity and mortality of CKD, emphasizing the need for defining and establishing …
morbidity and mortality of CKD, emphasizing the need for defining and establishing …