The pro-inflammatory immune response driven by microglia is a key contributor to the
pathogenesis of several neurodegenerative diseases. Though the research of microglia …

Ferroptosis is a newly discovered form of cell death that is featured in a wide range of
diseases. Exosome therapy is a promising therapeutic option that has attracted much …

Aims After a myocardial infarction, the adult human heart lacks sufficient regenerative
capacity to restore lost tissue, leading to heart failure progression. Finding novel ways to …

The long history of discovery and recently encouraging studies of the anti-cancer effect of
aspirin promise a closer step to widely used aspirin-based medication in cancer therapy. To …

Ischemic diseases including myocardial infarction (MI) and limb ischemia are some of the
greatest causes of morbidity and mortality worldwide. Cell therapy is a potential treatment …

Tissue engineering and regenerative medicine utilize mesenchymal stem cells (MSCs) and
their secretome in efforts to create or induce functional tissue replacement. Exosomes are …

A primary focus of pharmacology is the accurate transport of drugs from the peripheral veins
and their delivery to specific tissues and organs. Exosomes are nanoscale extracellular …

Heart diseases are the primary cause of mortality and morbidity worldwide which inflict a
heavy social and economic burden. Among heart diseases, most deaths are due to …

Exosomes have been described as nanoscale membranous extracellular vesicles that
emerge from a variety of cells and tissues and are enriched with biologically active genomic …

Cardiovascular diseases (CVDs) are one of the leading causes of morbidity and mortality.
Standard therapies have failed to significantly increase patients' survival. Moreover, the …