Enzymatic synthesis of enantiopure alcohols: current state and perspectives

BS Chen, FZR de Souza - RSC advances, 2019 - pubs.rsc.org
Enantiomerically pure alcohols, as key intermediates, play an essential role in the
pharmaceutical, agrochemical and chemical industries. Among the methods used for their …

Efficient whole-cell biosynthesis of (S)-2-chloro-1-(3, 4-difluorophenyl)-ethanol from 2-chloro-1-(3, 4-difluorophenyl) ethanone in a sustainable reaction system

L Kong, B Fan, YC He - Molecular Catalysis, 2023 - Elsevier
Abstract (S)-2-Chloro-1-(3, 4-difluorophenyl)-ethanol [(S)-CFPL] is a key chiral intermediate
in the manufacture of Ticagrelor. In this study, deep eutectic solvent (DES) was used as the …

[图书][B] Studies in natural products chemistry

A Rahman - 2023 - books.google.com
Studies in Natural Products Chemistry, Volume 79 covers the synthesis, testing and
recording of the medicinal properties of natural products, providing cutting-edge accounts of …

Biotransformation in the production of secondary metabolites

S Otles, VH Özyurt - Studies in natural products chemistry, 2021 - Elsevier
Secondary metabolites that can be produced from primary ones are not directly involved in
the normal growth, development, and reproduction of the organism. They are molecules that …

Green synthesis of chiral aromatic alcohols with Lactobacillus kefiri P2 as a novel biocatalyst

Y Baydaş, E Dertli, E Şahin - Synthetic Communications, 2020 - Taylor & Francis
Biocatalytic reduction is a very important field of research in synthetic organic chemistry.
Herein, three different Lactic Acid Bacteria (LAB) strains were evaluated for their …

Microbial species playing roles for the production of traditional Kasar cheese during pre-maturation period

A Yuvaşen, E Macit, E Dertli - LWT, 2018 - Elsevier
The microbial flora of traditional Kaşar cheese samples obtained from six dairy plants during
pre-maturation period of Kaşar maturation was analysed. In total, 500 isolates of none …

Hypouricemic, anti-inflammatory, and antioxidant activities of Lactobacillus-based functional yogurt in induced-arthritic male Wistar rats: Therapeutic and protective …

AN El-Dein, A Ezzat, HF Aly, EA Younis… - Biocatalysis and …, 2023 - Elsevier
Hyperuricemia is the increased serum uric acid concentration, associated with metabolic
syndrome that commonly leads to heart disease, gout, and chronic nephropathy. In animals …

Synthesis of enantiopure (S)‐6‐chlorochroman‐4‐ol using whole‐cell Lactobacillus paracasei biotransformation

E Şahin - Chirality, 2020 - Wiley Online Library
Chromane, which has a fused cyclic structure, is a significant molecule that can be found in
the structure of many important compounds. Lactobacillus paracasei BD101 was …

Green and scalable synthesis of chiral aromatic alcohols through an efficient biocatalytic system

MN Han, XM Wang, CH Pei, C Zhang… - Microbial …, 2021 - Wiley Online Library
Chiral aromatic alcohols have received much attention due to their widespread use in
pharmaceutical industries. In the asymmetric synthesis processes, the excellent …

Production of enantiopure chiral aryl heteroaryl carbinols using whole‐cell Lactobacillus paracasei biotransformation

E Şahin - Synthetic Communications, 2020 - Taylor & Francis
Aryl and heteroaryl chiral carbinols are useful precursors in the synthesis of drugs.
Lactobacillus paracasei BD87E6, which is obtained from a cereal based fermented …