Advances in cancer biology are revealing the importance of the cancer cell
microenvironment on tumorigenesis and cancer progression. Hyaluronan (HA), the main …

The functional complexity of higher organisms is not easily accounted for by the size of their
genomes. Rather, complexity appears to be generated by transcriptional, translational, and …

Receptor for hyaluronic acid-mediated motility (RHAMM) is a cell surface receptor for
hyaluronic acid that is critical for cell migration and a cell cycle protein involved in …

Although the literature about the functions of hyaluronan and the CD44 receptor in the brain
and brain tumours is extensive, the role of the receptor for hyaluronan-mediated motility …

Background and Objective: Hepatocellular carcinoma (HCC) is a highly aggressive
malignant tumor of the digestive system worldwide. Chronic hepatitis B virus (HBV) infection …

Simple Summary Since the discovery of the WarBurg effect, the veil of the tumorigenic role of
lactic acid has been gradually revealed. Recently, it was proposed that lactic acid that is …

Background Hepatocellular carcinoma (HCC) is one of the main causes of cancer-
associated deaths globally, accounts for 90% of primary liver cancers. However, further …

The maternal liver is challenged by metabolic demands throughout pregnancy. However,
hepatocyte dynamics and their physiological significance in pregnancy remain unclear …

Hepatocellular carcinoma (HCC) acquires an immunosuppressive microenvironment,
leading to unbeneficial therapeutic outcomes. Hyaluronan-mediated motility receptor …

Non-alcoholic steatohepatitis (NASH) is a type of nonalcoholic fatty liver disease and has
become a major risk factor for hepatocellular carcinoma (HCC). However, the underlying …