Alzheimer's disease (AD) is a complex age-related neurodegenerative disease, associated
with central and peripheral metabolic anomalies, such as impaired glucose utilization and …

Temperature changes and periods of detrimental cold occur frequently for many organisms
in their natural habitats. Homeothermic animals have evolved metabolic adaptation …

Environmental exposures during early life play a critical role in life-course health, yet the
molecular phenotypes underlying environmental effects on health are poorly understood. In …

Background The adipocyte hormone adiponectin improves insulin sensitivity and there is an
inverse correlation between adiponectin levels and type-2 diabetes risk. Previous research …

Objectives To examine the effects of a selective peroxisome proliferator-activated receptor
(PPAR-α) agonist treatment on interscapular brown adipose tissue (iBAT) whitening …

Excessive fatty acids and glucose uptake support the infiltration of adipose tissue (AT) by a
variety of immune cells including neutrophils, pro-inflammatory M1 macrophages, and mast …

In recent years, there has been an explosion in our understanding of adipose tissue biology.
Fat tissue is no longer regarded as a tissue the sole function of which is to store energy in …

Simple Summary The search for genomic regions related to adaptive abilities preserved in
the chicken gene pool of two breeds, which have not been under intensive selection …

Adiponectin is an adipokine predominantly produced by fat cells, circulates and exerts
insulin-sensitizing, cardioprotective and anti-inflammatory effects. Dysregulation of …

Obesity is a global public health issue. Thermogenesis is a novel way to promote anti-
obesity by consuming energy as heat rather than storing it as triacylglycerols. The browning …