Epithelial cells repress epithelial characteristics and elaborate mesenchymal characteristics
to migrate to other locations and acquire new properties. Epithelial plasticity responses are …

During development and in the context of different morphogenetic events, epithelial cells
undergo a process called epithelial to mesenchymal transition or transdifferentiation (EMT) …

Metastasis is the leading cause of cancer-associated death in most tumor types. Metastatic
dissemination of cancer cells from the primary tumor is believed to be initiated by the …

Chronic inflammation-promoted metastasis has been considered as a major challenge in
cancer therapy. Pro-inflammatory cytokine TNFα can induce cancer invasion and metastasis …

Biological processes that drive cell growth are exciting targets for cancer therapy. The
fibroblast growth factor (FGF) signaling network plays a ubiquitous role in normal cell …

Prostate cancer is a main urological disease associated with significant morbidity and
mortality. Radical prostatectomy and radiotherapy are potentially curative for localized …

Epithelial-mesenchymal transition (EMT) is a complex process in which epithelial cells
acquire the characteristics of invasive mesenchymal cells. EMT has been implicated in …

Metastatic dissemination is often initiated by the reactivation of an embryonic development
program referred to as epithelial-mesenchymal transition (EMT). The transcription factor …

MicroRNAs (miRNAs) have been shown to be dysregulated in virus-related cancers;
however, miRNA regulation of virus-related cancer development and progression remains …

Transforming growth factor (TGF)-β regulates a wide variety of cellular responses, including
cell growth arrest, apoptosis, cell differentiation, motility, invasion, extracellular matrix …