Cryptococcosis: epidemiology, fungal resistance, and new alternatives for treatment

FP Gullo, SA Rossi, JCO Sardi, VLI Teodoro… - European journal of …, 2013 - Springer
Cryptococcosis is an important systemic mycosis and the third most prevalent disease in
human immunodeficiency virus (HIV)-positive individuals. The incidence of cryptococcosis is …

Methods of Controlling Invasive Fungal Infections Using CD8+ T Cells

PR Kumaresan, TA Da Silva… - Frontiers in …, 2018 - frontiersin.org
Invasive fungal infections (IFIs) cause high rates of morbidity and mortality in
immunocompromised patients. Pattern-recognition receptors present on the surfaces of …

Current trends to control fungal pathogens: exploiting our knowledge in the host-pathogen interaction

LC García-Carnero, LA Pérez-García… - Infection and Drug …, 2018 - Taylor & Francis
Human fungal infections remain a major challenge in medicine. Only a limited number of
antifungal drugs are available, which are often related to severe adverse effects. In addition …

Adjuvants and delivery systems for antifungal vaccines: current state and future developments

DLF Portuondo, LS Ferreira, AC Urbaczek… - …, 2014 - academic.oup.com
Mycoses are gaining increasing attention in modern medicine because of the increase in
diseases associated with opportunistic fungal infections. Despite the recognized role of the …

Epitope‐Based Immunoinformatic Approach on Heat Shock 70 kDa Protein Complex of Cryptococcus neoformans var. grubii

RM Elhassan, NM Alsony, KM Othman… - Journal of …, 2021 - Wiley Online Library
Introduction. Cryptococcosis is a ubiquitous opportunistic fungal disease caused by
Cryptococcus neoformans var. grubii. It has high global morbidity and mortality among HIV …

Nanotechnological approaches for genetic immunization

AK Goyal, G Rath, T Garg - … in medicine: diagnosis and treatment of …, 2013 - Springer
Genetic immunization is one of the important findings that provide multifaceted
immunological response against infectious diseases. With the advent of r-DNA technology, it …

Antifungal efficacy of amphotericin B encapsulated fibrin microsphere for treating Cryptococcus neoformans infection in Swiss albino mice

AA Khan, M Jabeen, AM Alanazi… - Brazilian Journal of …, 2016 - SciELO Brasil
A natural and biocompatible fibrin microsphere is one of the most promising dual delivery
vehicle as compared to other traditionally designed delivery modalities. It represents …

Additive potential of combination therapy against cryptococcosis employing a novel amphotericin B and fluconazole loaded dual delivery system

AA Khan, AM Alanazi, M Jabeen, S Khan… - European Journal of …, 2018 - Elsevier
Cryptococcus neoformans is one of the most lethal fungi causing mortality across the globe.
Immuno-competent patients and patients taking immuno-suppressive medications are …

Enhanced Efficacy of Thiosemicarbazone derivative-encapsulated fibrin liposomes against candidiasis in murine model

AA Khan, AM Alanazi, N Alsaif, N Algrain, TA Wani… - Pharmaceutics, 2021 - mdpi.com
Candida albicans is the most studied species for the candidiasis infection and is becoming
resistant towards existing antifungal drugs. Considering this, in the current study, we …

[PDF][PDF] Avaliação das subpopulações de linfócitos T CD8+ em pacientes com paracoccidioidomicose

LDEO COSER - repositorio.unicamp.br
As células T CD8+ são caracterizadas pela sua capacidade citotóxica, mediada pela
liberação de grânulos citotóxicos ou por meio da ligação da molécula FasL, que resulta na …