A comprehensive comparative review of sequence-based predictors of DNA-and RNA-binding residues

J Yan, S Friedrich, L Kurgan - Briefings in bioinformatics, 2016 - academic.oup.com
Motivated by the pressing need to characterize protein–DNA and protein–RNA interactions
on large scale, we review a comprehensive set of 30 computational methods for high …

An overview of the prediction of protein DNA-binding sites

J Si, R Zhao, R Wu - International journal of molecular sciences, 2015 - mdpi.com
Interactions between proteins and DNA play an important role in many essential biological
processes such as DNA replication, transcription, splicing, and repair. The identification of …

TFClass: an expandable hierarchical classification of human transcription factors

E Wingender, T Schoeps, J Dönitz - Nucleic acids research, 2013 - academic.oup.com
Abstract TFClass (http://tfclass. bioinf. med. uni-goettingen. de/) provides a comprehensive
classification of human transcription factors based on their DNA-binding domains …

NCBRPred: predicting nucleic acid binding residues in proteins based on multilabel learning

J Zhang, Q Chen, B Liu - Briefings in bioinformatics, 2021 - academic.oup.com
The interactions between proteins and nucleic acid sequences play many important roles in
gene expression and some cellular activities. Accurate prediction of the nucleic acid binding …

Improving the prediction of protein–nucleic acids binding residues via multiple sequence profiles and the consensus of complementary methods

H Su, M Liu, S Sun, Z Peng, J Yang - Bioinformatics, 2019 - academic.oup.com
Motivation The interactions between protein and nucleic acids play a key role in various
biological processes. Accurate recognition of the residues that bind nucleic acids can …

Predicting protein-DNA binding residues by weightedly combining sequence-based features and boosting multiple SVMs

J Hu, Y Li, M Zhang, X Yang… - IEEE/ACM transactions …, 2016 - ieeexplore.ieee.org
Protein-DNA interactions are ubiquitous in a wide variety of biological processes. Correctly
locating DNA-binding residues solely from protein sequences is an important but …

DNAPred: accurate identification of DNA-binding sites from protein sequence by ensembled hyperplane-distance-based support vector machines

YH Zhu, J Hu, XN Song, DJ Yu - Journal of chemical information …, 2019 - ACS Publications
Accurate identification of protein–DNA binding sites is significant for both understanding
protein function and drug design. Machine-learning-based methods have been extensively …

HybridDBRpred: improved sequence-based prediction of DNA-binding amino acids using annotations from structured complexes and disordered proteins

J Zhang, S Basu, L Kurgan - Nucleic Acids Research, 2024 - academic.oup.com
Current predictors of DNA-binding residues (DBRs) from protein sequences belong to two
distinct groups, those trained on binding annotations extracted from structured protein-DNA …

A large-scale assessment of nucleic acids binding site prediction programs

Z Miao, E Westhof - PLoS computational biology, 2015 - journals.plos.org
Computational prediction of nucleic acid binding sites in proteins are necessary to
disentangle functional mechanisms in most biological processes and to explore the binding …

iProDNA-CapsNet: identifying protein-DNA binding residues using capsule neural networks

BP Nguyen, QH Nguyen, GN Doan-Ngoc… - BMC …, 2019 - Springer
Background Since protein-DNA interactions are highly essential to diverse biological events,
accurately positioning the location of the DNA-binding residues is necessary. This biological …