Highlighted advances in therapies for difficult-to-treat brain tumours such as glioblastoma

N Cruz, M Herculano-Carvalho, D Roque, CC Faria… - Pharmaceutics, 2023 - mdpi.com
Glioblastoma multiforme (GBM) remains a challenging disease, as it is the most common
and deadly brain tumour in adults and has no curative solution and an overall short survival …

Differential Impact of Valproic Acid on SLC5A8, SLC12A2, SLC12A5, CDH1, and CDH2 Expression in Adult Glioblastoma Cells

M Juknevičienė, I Balnytė, A Valančiūtė, MM Alonso… - Biomedicines, 2024 - mdpi.com
Valproic acid (VPA) has anticancer, anti-inflammatory, and epigenetic effects. The study
aimed to determine the expression of carcinogenesis-related SLC5A8, SLC12A2, SLC12A5 …

The comparative experimental study of sodium and magnesium dichloroacetate effects on pediatric PBT24 and SF8628 cell glioblastoma tumors using a chicken …

E Damanskienė, I Balnytė, A Valančiūtė… - International Journal of …, 2022 - mdpi.com
In this study, pyruvate dehydrogenase kinase-1 inhibition with dichloroacetate (DCA) was
explored as an alternative cancer therapy. The study's aim was to compare the effectiveness …

Impact of sodium dichloroacetate alone and in combination therapies on lung tumor growth and metastasis

A Al-Azawi, S Sulaiman, K Arafat, J Yasin… - International journal of …, 2021 - mdpi.com
Metabolic reprogramming has been recognized as an essential emerging cancer hallmark.
Dichloroacetate (DCA), an inhibitor of pyruvate dehydrogenase kinase (PDK), has been …

Natrio Valproato Įtaka Eksperimentiniams Plaučių Augliams

R Diržiuvienė - 2022 - search.proquest.com
............................................................................ 15 1.3. Valpro rūgštis (VPA).......................................
................................................... 15 1.4. Uretanas …

[引用][C] Tumors derived from lung cancer cells respond differently to treatment with sodium valproate (a HDAC inhibitor) in a chicken embryo chorioallantoic membrane …

R Diržiuvienė, L Šlekienė, J Palubinskienė… - 2022 - Universidad de Murcia …