The extracellular matrix (ECM) is a network of different proteins and proteoglycans that
controls differentiation, migration, repair, survival, and development, and it seems that its …

Disintegrins are non-enzymatic proteins that interfere on cell–cell interactions and signal
transduction, contributing to the toxicity of snake venoms and play an essential role in …

Background: The clinical efficacy of osteoporosis therapy is unsatisfactory. However, there is
currently no gold standard for the treatment of osteoporosis. Recent studies have indicated …

Background Both growth and nutritional traits are important economic traits of Crassostrea
gigas (C. gigas) in industry. But few work has been done to study the genetic architecture of …

ADAMTSs belong to the superfamily of secreted metalloendopeptidases, some of which are
reported to be closely associated with obesity. However, the role of ADAMTS15 is not well …

Nutritional traits that directly influence the flavor and nutritional value of the Pacific oyster,
Crassostrea gigas (C. gigas), are important economically for their commercial trade …

Abstract A Disintegrin and Metalloproteinase (ADAM) and A Disintegrin and
Metalloproteinase with Thrombospondin Motifs (ADAMTS) are two closely related families of …

Visceral adiposity is of greater risk than obesity in sc adipose tissue for diabetes and
cardiovascular disease. Its pathogenesis remains unclear, but it is associated with …

Objective A potential strategy to treat obesity–and the associated metabolic consequences–
is to increase energy expenditure. This could be achieved by stimulating thermogenesis …

Previous studies with gene-deficient mice (ADAMTS5-P) revealed that ADAMTS5 (A
Disintegrin And Metalloproteinase with Thrombospondin type 1 motifs, member 5) plays a …