The treatment of individual patients in cardiology practice increasingly relies on advanced
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …

Widely developed for clinical screening, electrocardiogram (ECG) recordings capture the
cardiac electrical activity from the body surface. ECG analysis can therefore be a crucial first …

Abstract Background and Objective: Cardiac electrophysiology is a medical specialty with a
long and rich tradition of computational modeling. Nevertheless, no community standard for …

Since myocardial fibers drive the electric signal propagation throughout the myocardium,
accurately modeling their arrangement is essential for simulating heart electrophysiology …

Models of cardiac tissue electrophysiology are an important component of the Cardiac
Physiome Project, which is an international effort to build biophysically based multi-scale …

The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

Background—Accurate knowledge of the human atrial fibrous structure is paramount in
understanding the mechanisms of atrial electric function in health and disease. Thus far …

Complex electrical activities in cardiac tissue can set up time-varying electromagnetic field.
Magnetic flux is introduced into the Fitzhugh-Nagumo model to describe the effect of …

Background Structural remodeling of human atria plays a key role in sustaining atrial
fibrillation (AF), but insufficient quantitative analysis of human atrial structure impedes the …

Key points We constructed a comprehensive mathematical model of the spontaneous
electrical activity of a human sinoatrial node (SAN) pacemaker cell, starting from the recent …