Among the 3 billion base pairs of the human genome, there are∼ 30,000–40,000 protein-
coding genes, but the function of at least half of them remains unknown. A new tool—short …

A recent revolution in RNA biology has led to the identification of new RNA classes with
unanticipated functions, new types of RNA modifications, an unexpected multiplicity of …

Experimental introduction of RNA into cells can be used in certain biological systems to
interfere with the function of an endogenous gene,. Such effects have been proposed to …

RNA interference (RNAi) is the process of sequence-specific, post-transcriptional gene
silencing in animals and plants, initiated by double-stranded RNA (dsRNA) that is …

Double-stranded RNA (dsRNA) induces sequence-specific posttranscriptional gene
silencing in many organisms by a process known as RNA interference (RNAi). Using a …

A serious shortcoming of many insecticides is that they can kill non-target species. To
address this issue, we harnessed the sequence specificity of RNA interference (RNAi) to …

Short interfering RNAs (siRNAs) are double-stranded RNAs of≈ 21–25 nucleotides that
have been shown to function as key intermediaries in triggering sequence-specific RNA …

RNA interference (RNAi) refers to the process of exogenous double‐stranded RNA (dsRNA)
silencing the complementary endogenous messenger RNA. RNAi has been widely used in …

Short interfering RNAs can be used to silence gene expression in a sequence-specific
manner in a process that is known as RNA interference. The application of RNA interference …

Animal cells have recently been shown to express a range of∼ 22 nucleotide noncoding
RNAs termed micro RNAs (miRNAs). Here, we show that the human mir-30 miRNA can be …