Increasing antibiotic resistance in multidrug-resistant (MDR) Gram-negative bacteria (MDR-
GNB) presents significant health problems worldwide, since the vital available and effective …

Colistin has been extensively used since the middle of the last century in animals,
particularly in swine, for the control of enteric infections. Colistin is presently considered the …

Colistin represents one of the few available drugs for treating infections caused by
carbapenem-resistant Enterobacteriaceae. As such, the recent plasmid-mediated spread of …

The polymyxin antibiotic colistin has been used in decades for treatment and prevention of
infectious diseases in livestock. Nowadays, it is even considered as last-line treatment …

Transposition is a major mechanism of horizontal gene mobility in prokaryotes. However,
exploration of the genes mobilized by transposons (cargo) is hampered by the difficulty in …

Background Azithromycin (AZM), sold under the name Zithromax, is classified as a
macrolide. It has many benefits due to its immunomodulatory, anti‐inflammatory, and …

The popularity of hydrogel membrane as wound dressing lies in its elastic physical
properties and the ability to encapsulate drug particles with improved properties to meet the …

The human microbiome emerges as a promising reservoir for diagnostic markers and
therapeutics. Since host-associated microbiomes at various body sites differ and diseases …

Purpose Carbapenem-resistant Enterobacterales bloodstream infections (CRE BSIs) have a
high mortality. However, an optimal antimicrobial treatment has not been determined. This …

The emerging resistance of Gram-negative bacteria is a growing problem worldwide.
Together with the financial cost, limited efficacy, and local unavailability of newer antibiotics …