Precision psychiatry is an emerging field with transformative opportunities for mental health.
However, the use of clinical prediction models carries unprecedented ethical challenges …

People with psychotic disorders can show marked interindividual variations in the onset of
illness, responses to treatment and relapse, but they receive broadly similar clinical care …

Individuals at clinical high risk (CHR) for psychosis have been found to have altered
cytokine levels, but whether these changes are related to clinical outcomes remains unclear …

Lipids are essential for cellular functioning considering their role in membrane composition,
signaling, and energy metabolism. The brain is the second most abundant organ in terms of …

Accumulating evidence suggests individuals with psychotic disorder show abnormalities in
metabolic and inflammatory processes. Recently, several studies have employed blood …

After five waves of coronavirus disease 2019 (COVID-19) outbreaks, it has been recognized
that a significant portion of the affected individuals developed long-term debilitating …

Abstract Background and Hypothesis Multiple lines of clinical, biochemical, and genetic
evidence suggest that disturbances of membrane lipids and their metabolism are probably …

Current strategies to predict psychosis identify only a small proportion of individuals at risk.
Additional strategies are needed to increase capacity for prediction and prevention of …

Ether phospholipid compositions are altered in the plasma or brain of patients with brain
disorders, such as Alzheimer and Parkinson's disease, including those with psychiatric …

Despite strong evidence of the neurodevelopmental origins of psychosis, current
pharmacological treatment is not usually initiated until after a clinical diagnosis is made, and …