Discovery of BAY 2413555, First Selective Positive Allosteric Modulator of the M2 Receptor to Restore Cardiac Autonomic Balance
A Vakalopoulos, D Basting, M Brechmann… - Journal of Medicinal …, 2024 - ACS Publications
Autonomic disbalance, ie, sympathetic overactivation and parasympathetic withdrawal, is a
causal driver of disease progression in heart failure. While sympatholytic drugs are …
causal driver of disease progression in heart failure. While sympatholytic drugs are …
7-substituted 1-aryl-naphthyridine-3-carboxylic acid amides and use thereof
H Teller, A Vakalopoulos, MB ARAPINIS… - US Patent …, 2021 - Google Patents
2019-03-19 Assigned to BAYER PHARMA AKTIENGESELLSCHAFT, BAYER
AKTIENGESELLSCHAFT reassignment BAYER PHARMA AKTIENGESELLSCHAFT …
AKTIENGESELLSCHAFT reassignment BAYER PHARMA AKTIENGESELLSCHAFT …
7-substituted 1-pyridyl-naphthyridine-3-carboxylic acid amides and use thereof
H Teller, MB ARAPINIS, A Vakalopoulos… - US Patent …, 2019 - Google Patents
2019-09-20 Assigned to BAYER AKTIENGESELLSCHAFT reassignment BAYER
AKTIENGESELLSCHAFT ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
AKTIENGESELLSCHAFT ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
Compositions and methods of using nintedanib for treating ocular diseases with abnormal neovascularization
J Ni, R Yang - US Patent 11,911,379, 2024 - Google Patents
(201301); 461 K 45/06 (201301); 461K 47/02 (*) Notice: Subject to any disclaimer, the term
of this (2013 01); 461K 47/10 (201301); 461 K patent is extended or adjusted under 35 …
of this (2013 01); 461K 47/10 (201301); 461 K patent is extended or adjusted under 35 …
Platelet aggregation inhibitor, preparation and uses thereof
S Wang, Y Lei, B Zhang - US Patent 11,713,300, 2023 - Google Patents
This disclosure relates to medicines, and more particularly to a platelet aggregation inhibitor,
a pharmaceutical composition containing the same and a preparation and application …
a pharmaceutical composition containing the same and a preparation and application …
7-substituted 1-aryl-naphthyridine-3-carboxylic acid amides and use thereof
H Teller, A Vakalopoulos, MB ARAPINIS… - US Patent …, 2022 - Google Patents
2021-04-01 Assigned to BAYER AKTIENGESELLSCHAFT, BAYER PHARMA
AKTIENGESELLSCHAFT reassignment BAYER AKTIENGESELLSCHAFT ASSIGNMENT …
AKTIENGESELLSCHAFT reassignment BAYER AKTIENGESELLSCHAFT ASSIGNMENT …