Atypical femur fractures: review of epidemiology, relationship to bisphosphonates, prevention, and clinical management

DM Black, B Abrahamsen, ML Bouxsein… - Endocrine …, 2019 - academic.oup.com
Bisphosphonates (BPs) are highly effective in treating osteoporosis and reducing hip,
vertebral, and other fractures by as much as 50% to 70%. However, since 2006, atypical …

Current understanding of epidemiology, pathophysiology, and management of atypical femur fractures

J Starr, YKD Tay, E Shane - Current osteoporosis reports, 2018 - Springer
Abstract Purpose of Review To summarize reports published since the 2013 American
Society of Bone and Mineral Research Task Force Report on atypical femoral fractures …

[HTML][HTML] The effect of osteoporosis and its treatment on fracture healing a systematic review of animal and clinical studies

EA Gorter, CR Reinders, P Krijnen… - Bone reports, 2021 - Elsevier
Introduction Osteoporosis is characterised by low bone mass and micro-architectural
deterioration of bone structure. Its treatment is directed at the processes of bone formation or …

Medical management of patients after atypical femur fractures: a systematic review and recommendations from the European Calcified Tissue Society

DM van de Laarschot, MJ McKenna… - The Journal of …, 2020 - academic.oup.com
Abstract Context Atypical femur fractures (AFFs) are serious adverse events associated with
bisphosphonates and often show poor healing. Evidence acquisition We performed a …

The effect of teriparatide on fracture healing after atypical femoral fracture: a systematic review and meta-analysis

SE Byun, KJ Lee, WC Shin, NH Moon… - Osteoporosis International, 2023 - Springer
Mini abstract This meta-analysis demonstrated that a greater prevalence of delayed union
and nonunion and a longer time to fracture healing in the group that did not receive TPTD …

Importance of bone turnover for therapeutic decisions in patients with CKD-MBD

SM Ott, HH Malluche, V Jorgetti, GJ Elder - Kidney International, 2021 - Elsevier
Patients with chronic kidney disease–mineral and bone disorder (CKD-MBD) frequently
have low bone formation rates. A recent review suggested that adynamic bone disease is …

The effects of teriparatide on acceleration of bone healing following atypical femoral fracture: comparison between daily and weekly administration

H Tsuchie, N Miyakoshi, K Iba, Y Kasukawa… - Osteoporosis …, 2018 - Springer
We compared the effectiveness of promoting bone healing between two teriparatide
preparations for atypical femoral fracture (AFF). A total of 45 AFFs were included in this …

Mechanisms underlying normal fracture healing and risk factors for delayed healing

C Cheng, D Shoback - Current Osteoporosis Reports, 2019 - Springer
Abstract Purpose of Review Substantial advances have been made in understanding the
biological basis of fracture healing. Yet, it is unclear whether the presence of osteoporosis or …

[HTML][HTML] Does teriparatide improve fracture union?: a systematic review

BH Yoon, KC Kim - Journal of bone metabolism, 2020 - ncbi.nlm.nih.gov
We conducted an updated review of the evidence of teriparatide (TPTD) for fracture healing
for the following questions.(1) Does it decrease fracture healing time?;(2) Can it be an …

Treatment strategy for atypical ulnar fracture due to severely suppressed bone turnover caused by long-term bisphosphonate therapy: a case report and literature …

K Abe, H Kimura, N Yamamoto, S Shimozaki… - BMC Musculoskeletal …, 2020 - Springer
Background Atypical fractures may occur due to the combined effect of severely suppressed
bone turnover (SSBT) caused by long-term bisphosphonate treatment and chronic repetitive …