Acute kidney injury (AKI) is a major clinical concern in sickle cell disease (SCD). Clinical
evidence suggests that red cell alarmins may cause AKI in SCD, however, the sterile …

In 2012, the US National Institutes of Health and the UK-based Wellcome Trust funded a US
$76 million initiative called Human Heredity and Health in Africa (H3Africa), in partnership …

Background Hemoglobinopathies, such as sickle cell disease (SCD), are inherited disorders
of hemoglobin (Hb) synthesis. SCD presents with complex clinical manifestations, including …

Study objectives were to examine the relationships between physical activity, pain, and
psychological distress in youth 8 to 17 years of age with sickle cell disease. Participants …

Abstract Sickle Cell Anaemia (SCA) is one of the most prevalent monogenic disorders. The
formation of polymerised haemoglobin leading to erythrocyte rigidity and appearance of …

Abstract Background and Aims Hemolysis is a fundamental feature of sickle cell disease
(SCD) contributing to the vaso‐occlusive crisis of patients. The objectives of the study were …

Background Sickle cell Anemia and/or Disease (SCA/SCD) is an autosomal recessive
disease leading to abnormal hemoglobin with global prevalence in general and tribal …

Aim: The aim of this study was to evaluate changes in some haematological parameters in
sickle cell anaemia subjects in Rivers State. Study Design: This study is a cross-sectional …

Aim: The aim of this study was to assess the influence of gender and subjects' condition on
haemostatic parameters in sickle cell anaemia and control subjects. Study Design: This …