[HTML][HTML] Pyroptosis: A new frontier in cancer
Y Fang, S Tian, Y Pan, W Li, Q Wang, Y Tang… - Biomedicine & …, 2020 - Elsevier
Pyroptosis is an inflammatory form of cell death triggered by certain inflammasomes, leading
to the cleavage of gasdermin D (GSDMD) and activation of inactive cytokines like IL-18 and …
to the cleavage of gasdermin D (GSDMD) and activation of inactive cytokines like IL-18 and …
Strategies to access biosynthetic novelty in bacterial genomes for drug discovery
F Hemmerling, J Piel - Nature Reviews Drug Discovery, 2022 - nature.com
Bacteria provide a rich source of natural products with potential therapeutic applications,
such as novel antibiotic classes or anticancer drugs. Bioactivity-guided screening of …
such as novel antibiotic classes or anticancer drugs. Bioactivity-guided screening of …
Current levels of microplastic pollution impact wild seabird gut microbiomes
Microplastics contaminate environments worldwide and are ingested by numerous species,
whose health is affected in multiple ways. A key dimension of health that may be affected is …
whose health is affected in multiple ways. A key dimension of health that may be affected is …
Marine bacteria as source of antimicrobial compounds
P Stincone, A Brandelli - Critical reviews in biotechnology, 2020 - Taylor & Francis
The marine environment encompasses a huge biological diversity and can be considered
as an underexplored location for prospecting bioactive molecules. In this review, the current …
as an underexplored location for prospecting bioactive molecules. In this review, the current …
Production of plant natural products through engineered Yarrowia lipolytica
A Muhammad, X Feng, A Rasool, W Sun, C Li - Biotechnology Advances, 2020 - Elsevier
Plant natural products have broad applications in the pharmaceutical, food, cosmetics and
flavor industries. However, the current manufacturing methods for plant natural products …
flavor industries. However, the current manufacturing methods for plant natural products …
Ecological and biotechnological importance of secondary metabolites produced by coral‐associated bacteria
Symbiotic relationships between corals and their associated micro‐organisms are essential
to maintain host homeostasis. Coral‐associated bacteria (CAB) can have different beneficial …
to maintain host homeostasis. Coral‐associated bacteria (CAB) can have different beneficial …
Symbiosis-inspired approaches to antibiotic discovery
Covering: 2010 up to 2017 Life on Earth is characterized by a remarkable abundance of
symbiotic and highly refined relationships among life forms. Defined as any kind of close …
symbiotic and highly refined relationships among life forms. Defined as any kind of close …
Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights
Covering: up to 2017 The overwhelming majority of antibiotics in clinical use originate from
Gram-positive Actinobacteria. In recent years, however, Gram-negative bacteria have …
Gram-positive Actinobacteria. In recent years, however, Gram-negative bacteria have …
Marine pharmacology in 2016–2017: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis and antiviral …
AMS Mayer, AJ Guerrero, AD Rodríguez… - Marine drugs, 2021 - mdpi.com
The review of the 2016–2017 marine pharmacology literature was prepared in a manner
similar as the 10 prior reviews of this series. Preclinical marine pharmacology research …
similar as the 10 prior reviews of this series. Preclinical marine pharmacology research …
The influence of bacteria on animal metamorphosis
The swimming larvae of many marine animals identify a location on the seafloor to settle and
undergo metamorphosis based on the presence of specific surface-bound bacteria. While …
undergo metamorphosis based on the presence of specific surface-bound bacteria. While …