Radiotherapy has become a critical component for the treatment of all stages and types of
lung cancer, often times being the primary gateway to a cure. However, given that radiation …

A deep neural network is proposed for solving the dynamic image reconstruction problems
in electrical impedance tomography (EIT), which can realize the filtering, smoothing, and …

Objective. Most methods for partial volume correction (PVC) of positron emission
tomography (PET) data employ anatomical segmentation of images into regions of interest …

Background Accurate quantification of PET studies depends on the spatial resolution of the
PET data. The commonly limited PET resolution results in partial volume effects (PVE) …

A wide range of buprenorphine doses are used for either pain management or maintenance
therapy in opioid addiction. The complex in vitro profile of buprenorphine, with affinity for µ …

The quality of reconstructed dynamic PET images, as well as the statistical reliability of the
estimated pharmacokinetic parameters is often compromised by high levels of statistical …

Background Modafinil, a nonamphetaminic wake-promoting compound, is prescribed as first
line therapy in narcolepsy, an invalidating disorder characterized by excessive daytime …

Longitudinal mouse PET imaging is becoming increasingly popular due to the large number
of transgenic and disease models available but faces challenges. These challenges are …

This review discusses the use of stable (13C, 2D) or radioactive isotopes (14C, 11C, 18F,
131I, 64Cu, 68Ga) incorporated into the molecular structure of new drug entities for the …

Purpose PET and SPECT voxel kinetics are highly noised. To our knowledge, no study has
determined the effect of denoising on the ability to detect differences in binding at the voxel …